Bausch Health Americas, Inc.

This study tests a single dose of brodalumab in children aged 6 to 17 with severe plaque psoriasis. The goal is to see how safe the drug is and how the body processes it. Only 2 children are enrolled, making this a very early look at the drug's effects in younger patients.

This study is tracking 3500 adults with moderate-to-severe psoriasis to compare the long-term safety of brodalumab with other psoriasis treatments. Researchers are specifically looking at rates of cancer (excluding skin cancer) in people taking brodalumab versus those on other bi…

This study planned to test an inhaled medicine called Virazole (ribavirin) in adults hospitalized with COVID-19 who had serious breathing trouble. The goal was to see if the drug was safe and could improve oxygen levels. However, the trial was withdrawn before enrolling any volun…

This Phase 3 study tests whether a special form of the antibiotic rifaximin can delay the first episode of overt hepatic encephalopathy (brain dysfunction) in people with liver cirrhosis who have controlled fluid buildup in the belly. About 466 participants will receive either ri…

This trial tests whether plecanatide, a drug taken by mouth once a day, can safely improve bowel movements in children and adolescents aged 6 to 17 with functional constipation. Participants receive either low-dose plecanatide, high-dose plecanatide, or a placebo for 8 weeks. The…

This study is testing a next-generation Fraxel laser system to see how well it improves skin issues like sun damage, lesions, and wrinkles around the eyes. About 49 adults aged 21 to 60 will receive up to three laser treatments. Researchers will check for improvements using a doc…

This study follows about 200 people aged 12 and older in Canada who are using a prescription gel containing clindamycin, adapalene, and benzoyl peroxide for acne. Researchers want to see how satisfied patients are, how well they stick to the treatment, and how it affects their qu…

This Canadian study follows about 394 adults with plaque psoriasis who are starting brodalumab as part of their regular care. Over 12 months, researchers measure changes in skin-related quality of life, work productivity, and treatment satisfaction. The goal is to understand how …

This study follows 8,000 children aged 2 to 17 with eczema who have used Elidel cream (pimecrolimus 1%). Over 10 years, researchers track how many develop cancer, especially lymphoma and thyroid cancer. The goal is to see if the cream raises cancer risk. No new treatment is given…