Anrs, Emerging Infectious Diseases

This study tests whether a combination of two antiviral drugs (sofosbuvir and daclatasvir) can cure hepatitis C in children aged 6 and older and adolescents in Cambodia. About 21,000 participants will take the medication and be checked 12 weeks after stopping to see if the virus …

This early-stage trial tests a new booster vaccine called CD40.Pan.CoV in 48 healthy adults in France. The goal is to see if it is safe and can boost the body's immune defenses against several coronavirus variants. Participants receive one injection and are monitored for side eff…

This study tests a community-based approach to screen and treat hepatitis C in people who use drugs across four French cities. Around 3,400 participants will be tested and offered treatment, with the goal of curing the infection. The program also looks at mental health and addict…

This study tests whether a structured exercise program can improve physical function and reduce disability in HIV-positive adults over 50 in Ivory Coast. Participants are randomly assigned to a supervised group exercise, a home-based program with phone support, or health educatio…