Anrs, Emerging Infectious Diseases

This study tests a new booster vaccine called CD40.Pan.CoV in 48 healthy adults in France. The goal is to see if it is safe and can boost the body's defenses against multiple coronavirus variants. Participants receive one injection and are monitored for side effects and immune re…

This study tests whether the antiviral drug tecovirimat can help people with monkeypox heal faster. About 480 adults and teens (14+) with active lesions will receive either tecovirimat or a placebo, alongside standard care. The main goal is to see how quickly skin and mouth sores…

This study is testing a combination of two antiviral drugs, sofosbuvir and daclatasvir, in children aged 6 and older with active hepatitis C in Cambodia. The goal is to see if the treatment can clear the virus from the blood 12 weeks after finishing the 12-week course. The trial …

This study aims to eliminate hepatitis C among people who use drugs in Paris, Marseille, Lyon, and Fort-de-France. Researchers will screen participants, provide immediate treatment, and use a peer-referral system to reach more people. The goal is to see if this community-based ap…

This study tests whether a 48-week exercise program can improve physical function and reduce disability in HIV-positive adults over 50 in Côte d'Ivoire. 180 participants will be split into three groups: supervised group exercise, home-based exercise with phone support, or health …