Anrs, Emerging Infectious Diseases

This study tests whether giving the Ervebo vaccine together with Inmazeb antibodies can safely prevent Ebola in healthy adults. The vaccine works slowly, while antibodies act fast, so researchers want to see if they interfere with each other. About 132 volunteers will receive dif…

This study tests whether giving a combination of a vaccine (Ervebo) and an antibody drug (Inmazeb) right after exposure to Ebola can prevent the disease better than the vaccine alone. It involves 160 people who have had close contact with an Ebola patient, such as touching their …

This study looks at frailty and other age-related health problems in 600 older adults (60+) in Burkina Faso, Côte d'Ivoire, and Togo. Half have HIV, half do not. Researchers want to see if HIV speeds up aging and find better ways to screen for and manage these issues. The goal is…

This study aims to find out how common Japanese Encephalitis (JE) virus is among children in Cambodia, both in those who are healthy and those hospitalized with fever and brain symptoms. Researchers will follow 4000 children aged 2-14, testing blood for signs of the virus. The go…

This study will follow over 5,000 pregnant women with HIV, hepatitis B, hepatitis C, or arbovirus infections, along with their children, for up to 7 years. Researchers aim to learn how often the virus passes from mother to child and how infections and treatments affect pregnancy,…