Aga Khan University

This study tests whether eating a balanced meal made from local foods once a day during pregnancy can help women in rural Pakistan handle heat stress better and have healthier babies. About 292 women will either eat this meal daily or continue their usual diet. Researchers will m…

This study tests whether adding an ultrasound-guided nerve block (Pecs block) to a ketamine infusion can prevent chronic pain after breast cancer surgery. 120 women scheduled for mastectomy will be randomly assigned to receive either ketamine alone or ketamine plus the nerve bloc…

This study tests a mobile app called m-LIfE designed to help sedentary bank employees in Pakistan become more active and eat better. Over 12 weeks, participants will receive daily reminders, tips, and tracking tools. The goal is to see if the app is practical and can encourage he…

This trial tests whether using ultrasound to guide a nerve-freezing procedure (radiofrequency ablation) is better than the standard X-ray-guided method for people with chronic knee osteoarthritis. Fifty-two adults over 50 with severe knee pain will be randomly assigned to one of …

This study tests whether acotiamide works better than itopride for people with functional dyspepsia, a condition causing fullness, pain, or burning after meals. About 368 adults will take one of the two pills three times daily for 4 weeks and track their symptoms. The goal is to …

This study tests whether a multicomponent support group can improve the confidence (self-efficacy) of primary caregivers of children with Duchenne muscular dystrophy or spinal muscular atrophy in Pakistan. Thirty caregivers will join group sessions with doctors, therapists, and o…

This trial aims to see if educational videos or audio messages can improve parents' knowledge and practices about retinopathy of prematurity (ROP) screening. About 99 parents of premature infants in Karachi will receive either a video, audio, or standard pamphlet. Their understan…

This study will observe 100 adults with chronic pain from abdominal or pelvic cancer to see how effective pain management interventions are. Researchers will track pain scores using a 0-10 scale and note any side effects or complications. The goal is to understand what works best…