New study tests safer way to zap knee pain without surgery

NCT ID NCT07475793

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether using ultrasound to guide a nerve-freezing procedure (radiofrequency ablation) is better than the standard X-ray-guided method for people with chronic knee osteoarthritis. Fifty-two adults over 50 with severe knee pain will be randomly assigned to one of the two methods. The goal is to see which approach provides greater pain relief and improved function over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency ablation

What this could lead to

If successful, this could show that ultrasound guidance is a better, safer way to perform nerve ablation for lasting knee pain relief.

What could go wrong

This is a small, early-stage trial with only 52 people. The pain relief is temporary (3-12 months) and the procedure may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••