WILSON DISEASE
Clinical trials for WILSON DISEASE explained in plain language.
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One-Shot gene therapy tested for rare copper disease
Disease control Recruiting nowThis is an early-stage study testing a single-dose gene therapy injection called LY-M003 for Wilson disease. The goal is to see if it is safe and if it can help the body properly process copper, potentially reducing the need for lifelong medications. The study will include a smal…
Matched conditions: WILSON DISEASE
Phase: EARLY_PHASE1 • Sponsor: Chaohui Yu • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Researchers probe link between rare liver disease and dental health
Knowledge-focused Recruiting nowThis study aims to understand how Wilson's disease affects oral health. Researchers will compare the dental health of 150 people with the disease to healthy volunteers, checking for cavities and gum problems. They will also test if copper levels in saliva can show how well the di…
Matched conditions: WILSON DISEASE
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Researchers investigate mysterious skin side effects of Wilson's disease medication
Knowledge-focused Recruiting nowThis study aims to better understand skin damage that can occur in Wilson's disease patients taking the standard medication D-Penicillamine. Researchers will compare skin elasticity in 120 participants—both patients on the medication and healthy volunteers—using silicone molds an…
Matched conditions: WILSON DISEASE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Researchers seek to replace cumbersome 24-Hour urine tests for rare liver disease
Knowledge-focused Recruiting nowThis study aims to make monitoring easier for people with Wilson's Disease, a genetic condition where too much copper builds up in the body. Researchers are testing if collecting urine during a shorter, specific 8-hour window at night gives the same information as the current dif…
Matched conditions: WILSON DISEASE
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC
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Researchers test simple urine check for Wilson's disease
Knowledge-focused Recruiting nowThis study aims to find a better way to monitor treatment for Wilson Disease, a condition where the body stores too much copper. Researchers will temporarily stop participants' standard medications for a few days to measure copper levels in their urine and blood. The goal is to s…
Matched conditions: WILSON DISEASE
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Hospital launches major effort to map the mysteries of rare diseases
Knowledge-focused Recruiting nowThis study aims to create a single, large registry to collect information on many different rare diseases. It will enroll about 380 patients already being treated at the Hospital Italiano de Buenos Aires who have one of the listed rare conditions. The goal is to gather data to be…
Matched conditions: WILSON DISEASE
Sponsor: Hospital Italiano de Buenos Aires • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:53 UTC
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Researchers ask wilson disease patients: would you try gene editing?
Knowledge-focused Recruiting nowThis study aims to prepare for future gene editing trials for Wilson Disease, a genetic disorder that causes copper to build up in the body. It will enroll about 30 adults with the disease to complete a survey about their experiences and their interest in potential gene editing t…
Matched conditions: WILSON DISEASE
Sponsor: Prime Medicine, Inc. • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:26 UTC