Saliva test may reveal hidden clues in Wilson's disease

NCT ID NCT05444127

Recruiting now Knowledge-focused Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at dental health and oral quality of life in people with Wilson's disease, comparing those with liver versus neurological symptoms to healthy controls. Researchers will collect saliva samples and use questionnaires and dental exams to see if copper levels in saliva reflect treatment effectiveness. The goal is to better understand oral health problems in Wilson's disease and find new ways to monitor the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better monitor Wilson's disease through saliva copper levels and improve dental care for patients.
What could go wrong: This is an observational study, not a treatment trial. It will not directly change how Wilson's disease is managed, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Wilson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

WILSON DISEASE

Contacts and locations

Locations

Fondation Adolphe de Rothschild
RECRUITING

Paris, 75019, France
Hopital Charles Foix
ACTIVE_NOT_RECRUITING

Ivry-sur-Seine, 94200, France
Hôpital Charles Foix
ACTIVE_NOT_RECRUITING

Ivry-sur-Seine, 94200, France

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