VULVAR CANCER
Clinical trials for VULVAR CANCER explained in plain language.
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New combo therapy shows promise for Hard-to-Treat vulvar cancer
Disease control OngoingThis study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (cisplatin) and radiation can shrink or control advanced vulvar cancer that cannot be removed by surgery. About 24 participants will receive this combination therapy. The goal is to see …
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 17, 2026 00:49 UTC
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New Triple-Drug attack aims to shrink Hard-to-Treat cancers
Disease control OngoingThis study tests a combination of three drugs (entinostat, PDS01ADC, and bintrafusp alfa) in adults with advanced cancers linked to HPV or certain colon cancers that haven't responded well to standard treatments. The goal is to find a safe dose and see if the combo can shrink tum…
Matched conditions: VULVAR CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 00:48 UTC
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New hope for advanced cancers: immunotherapy drug shows promise in large trial
Disease control OngoingThis study tested the drug pembrolizumab in over 1,600 people with various advanced solid tumors that had stopped responding to standard treatments. The goal was to see if the drug could shrink or control the tumors. The trial focused on identifying which patients were most likel…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Can a drug combo wake up 'Cold' tumors to immunotherapy?
Disease control TerminatedThis study tests whether combining two drugs (atezolizumab and tivozanib) can help the immune system attack cancers that usually don't respond to immunotherapy, like certain prostate, pancreatic, and breast cancers. About 29 adults with advanced or metastatic disease who have alr…
Matched conditions: VULVAR CANCER
Phase: PHASE1, PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New imaging technique could improve lymph node detection in vulvar cancer
Diagnosis OngoingThis study tests whether a special dye and camera (ICG-NIR imaging) can find sentinel lymph nodes as well as the standard method in people with early-stage vulvar cancer. About 22 participants will receive both imaging types during their planned surgery. The goal is to see if the…
Matched conditions: VULVAR CANCER
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated May 17, 2026 00:46 UTC
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Blood test may tame Chemo's nerve damage
Knowledge-focused TerminatedThis study looks at whether doctors can consistently measure the chemotherapy drug paclitaxel in the blood of cancer patients. The goal is to see if this could help adjust doses to kill cancer while reducing nerve damage, a common side effect. About 22 adults with various solid t…
Matched conditions: VULVAR CANCER
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 17, 2026 00:53 UTC
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Mid-Treatment PET scans could Fine-Tune radiation for cancer patients
Knowledge-focused OngoingThis study explores whether doing a PET scan during radiation therapy can help doctors adjust the treatment plan to improve outcomes for people with cervical, vulvar, esophageal, or anal cancer. About 90 adults will receive standard radiation plus an extra PET scan partway throug…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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New program aims to slash cancer wait times in botswana communities
Knowledge-focused OngoingThis study tests a program called Potlako+ that combines community education, help for healthcare workers, and patient guides to speed up cancer detection and treatment. About 874 adults in Botswana with cancer symptoms or at risk will take part. Half the communities get the prog…
Matched conditions: VULVAR CANCER
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC