VITILIGO

This study tested an investigational drug called AMG 714 to see if it could help restore skin color (repigmentation) in adults with vitiligo. The trial involved 60 participants and compared the drug against a placebo over 24 weeks. Researchers also looked at whether adding light …

This study compared two light-based treatments for vitiligo, a condition that causes loss of skin color. Researchers tested whether a newer blue light therapy works as well as the standard targeted UVB light treatment to help restore pigment in stable vitiligo patches. The trial …

This study tested if adding a high dose of the cholesterol-lowering drug atorvastatin to standard UVB light therapy could better control active vitiligo. It involved 28 adults whose vitiligo was actively spreading. For six months, one group received the drug plus light therapy, w…

This study tested whether using a new cream called ruxolitinib works better alone or when combined with other common skin creams (tacrolimus or a steroid) for treating vitiligo. 120 adults with non-segmental vitiligo covering less than 10% of their body used the assigned creams f…

This study tested if treating vitiligo very early could stop the disease from spreading and prevent the white patches from returning after treatment. 51 adults with different stages of vitiligo received a standard combination of UV light therapy and low-dose steroid pills for 6 m…

This study tested whether the drug tofacitinib is safe and effective for treating several common autoimmune skin conditions in adolescents and adults with Down syndrome. Researchers wanted to see if reducing overactive immune signaling could improve skin health, quality of life, …

This study tested if adding a weekly oral medication (methotrexate) to a standard light therapy treatment works better for controlling active vitiligo than light therapy alone. It involved 32 adults whose vitiligo was actively spreading. Researchers measured changes in skin color…

This study tested if adding a special antioxidant pill called GLISODIN to standard UVB light therapy works better for treating vitiligo than light therapy with a placebo pill. It involved 50 adults with widespread, non-segmental vitiligo. Researchers measured changes in the size …

This study aimed to understand the mental health risks for adults with vitiligo, a condition that causes skin to lose its pigment. Researchers compared over 36,000 UK adults with vitiligo to people without it to see if they were more likely to experience depression, anxiety, or o…

This was a small, completed lab study that tested whether specially engineered versions of a natural immune protein (called IL-2 muteins) could selectively boost a type of calming immune cell (regulatory T cells) taken from patients with various autoimmune and inflammatory diseas…

This study aimed to understand why vitiligo treatments work better on some body areas (like the face) than others (like hands and feet). Researchers collected small skin samples from 20 adults with vitiligo and healthy volunteers to compare the molecular activity in different loc…