VITILIGO

This study tests a daily pill called upadacitinib to see if it can safely bring back skin color in people with non-segmental vitiligo, a condition where the immune system attacks pigment cells. About 540 adults and teens will take either the drug or a placebo for 48 weeks, then e…

This study tests whether adding a tacrolimus or tyrosine cream to standard UVB light therapy helps restore skin color in adults with vitiligo. Sixty-seven participants will apply one of the creams twice daily and receive UVB twice a week for three months. The goal is to see which…

This early-stage trial tests a new drug called TEV-53408 in 38 adults with vitiligo, a condition that causes white patches on the skin. The main goal is to see if the drug is safe, with a secondary goal of checking how well it works. Participants receive the drug as a shot under …

This study tests an ointment called MH004 in 156 people aged 12 to 65 with non-segmental vitiligo, a condition that causes white patches on the skin. The goal is to see if the ointment can safely help bring back skin color, especially on the face. Participants apply the cream for…

This study tests the long-term safety and effectiveness of a daily pill called ritlecitinib for people with non-segmental vitiligo, a condition that causes white patches on the skin. About 394 adults and teens who already completed a year of treatment will either continue their c…

This study tests whether taking dexamethasone pills twice a week for 3 months can stop active vitiligo from spreading in children aged 4 to 9. Researchers will monitor skin activity, growth, and side effects like bone age changes or adrenal issues. The goal is to control the dise…

This study tests an experimental cream called SHR0302Base in 155 adults with nonsegmental vitiligo, a condition that causes white patches on the skin. The goal is to see if the cream can safely restore color, especially on the face and neck, compared to a cream without the active…

This study tests whether a cream containing rapamycin, applied daily for six months, can help bring back skin color in people with vitiligo. Twenty participants apply the cream to one patch of skin and a placebo to another, with doctors checking results at 2, 4, and 6 months. The…

This study is creating a large registry of 15,000 adults and children with inflammatory skin conditions like eczema, psoriasis, and vitiligo. Researchers will follow participants in regular clinics to see how well current and new treatments work and what side effects occur. The g…

This study looks at how a specific gene (TRPM2) and an inflammation-related protein (NLRP3) are linked in people with vitiligo, a condition that causes white patches on the skin. Researchers will compare blood samples from 60 adults with vitiligo and healthy volunteers to see if …