UNRESECTABLE UROTHELIAL CARCINOMA
Clinical trials for UNRESECTABLE UROTHELIAL CARCINOMA explained in plain language.
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Can a Two-Drug punch revive immunotherapy for tough bladder cancers?
Disease control Recruiting nowThis early-phase trial is testing whether adding an experimental drug called emavusertib (CA-4948) to the immunotherapy pembrolizumab can help patients with advanced urothelial cancer whose tumors have become resistant to PD-1/PD-L1 blockers. The study will enroll 27 adults and f…
Matched conditions: UNRESECTABLE UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 07:00 UTC
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New combo aims to outsmart resistant bladder cancer
Disease control Recruiting nowThis phase III trial tests whether combining two drugs—pembrolizumab (an immunotherapy) and sacituzumab govitecan (a targeted chemotherapy)—works better than standard chemotherapy for people with advanced bladder cancer that has stopped responding to initial immunotherapy. About …
Matched conditions: UNRESECTABLE UROTHELIAL CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, given alone or with the immunotherapy drug pembrolizumab. The goal is to see if the combination is safe and helps the immune system attack advanced solid tumors. About 132 people with various advanc…
Matched conditions: UNRESECTABLE UROTHELIAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug cocktail aims to shrink Hard-to-Treat bladder tumors
Disease control Recruiting nowThis early-phase trial is testing whether combining two drugs—cabozantinib and enfortumab vedotin—can safely treat advanced bladder cancer that has spread. About 32 adults whose cancer worsened after standard treatments will receive the combo. The study aims to find the best dose…
Matched conditions: UNRESECTABLE UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New hope for advanced bladder cancer: maintenance therapy after combo treatment
Disease control Recruiting nowThis study tests whether a maintenance drug (pembrolizumab) can help control advanced bladder cancer after an initial 18-week combination treatment. About 97 people who have not had prior therapy for metastatic disease will participate. The goal is to see if this approach improve…
Matched conditions: UNRESECTABLE UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Fox Chase Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Cancer patients may soon get immunotherapy at home instead of the clinic
Symptom relief Recruiting nowThis study compares giving the cancer drug nivolumab (Opdivo) as a shot at home versus in a clinic for people with various advanced cancers. The goal is to see if home treatment improves patients' overall care experience and quality of life. About 50 adults will receive the drug …
Matched conditions: UNRESECTABLE UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC