UNRESECTABLE SOLID TUMOR
Clinical trials for UNRESECTABLE SOLID TUMOR explained in plain language.
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Radioactive nanoparticles target Tough-to-Treat cancers in new trial
Disease control Recruiting nowThis is a first-in-human study testing a new experimental drug called 177Lu-SN201 in adults with advanced solid tumors that have progressed despite standard treatments. The drug is a radioactive nanoparticle designed to accumulate in tumors. The main goals are to find a safe and …
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Spago Nanomedical AB • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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First patients test new 'Smart Bomb' drug for advanced cancers
Disease control Recruiting nowThis is the first study in people to test a new drug called RLY-2608, which is designed to target a specific genetic mutation (PIK3CA) found in many advanced solid tumors and breast cancers. The main goals are to find the safest and most effective dose, check for side effects, an…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Relay Therapeutics, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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First-of-its-Kind cancer drug targets 'Guardian Gene' mutation
Disease control Recruiting nowThis is a first-in-human study testing a new drug called CLSP-1025 for adults with advanced solid tumors that have a specific genetic change called the p53 R175H mutation. The main goals are to find a safe dose and see if the drug can help control the cancer. The drug works by en…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Clasp Therapeutics, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug duo tested in fight against Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing the safety and initial effectiveness of combining two targeted cancer drugs, pemigatinib and afatinib, in people with advanced solid tumors that have specific genetic changes and have stopped responding to standard treatments. The main goals are …
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New drug targets 'Undruggable' cancer mutation in early human trial
Disease control Recruiting nowThis study is testing a new drug called FMC-376 for people with advanced solid tumors that have a specific genetic change called KRAS G12C. The main goals are to find a safe and effective dose and to see if the drug can shrink or control tumors. It is for patients whose cancer ha…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Frontier Medicines Corporation • Aim: Disease control
Last updated Mar 10, 2026 12:53 UTC
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New 'Peaks and Valleys' radiation aims to shrink tough tumors with fewer side effects
Symptom relief Recruiting nowThis early study is testing a specialized form of proton radiation called 'GRID' for patients with large, inoperable, or metastatic tumors that need treatment to relieve symptoms. The technique delivers radiation in a precise 'peaks and valleys' pattern, which researchers hope wi…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC