New drug DS1025a takes on advanced solid tumors in first human trial

NCT ID NCT07681882

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This trial is testing a new drug called DS1025a in people with advanced solid tumors that have spread, cannot be removed by surgery, or have stopped responding to other treatments. The main goals are to check the drug's safety, how the body processes it, and whether it shows any signs of shrinking tumors. This is the first time DS1025a is being tested in humans, so it is a small, early-stage study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DS1025a

What this could lead to

If safe and effective, DS1025a could offer a new treatment option for people with advanced solid tumors that have stopped responding to standard therapies.

What could go wrong

This is an early, small phase 1 trial focused on safety, so it is unknown if DS1025a will effectively shrink tumors or improve survival. Side effects are possible and will be closely monitored.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kansai Medical University Hospital

    Osaka, 573-1191, Japan

    Contact

  • National Cancer Center Hospital East

    Chiba, 277-8577, Japan

    Contact

  • The Cancer Institute Hospital of JFCR

    Tokyo, 135-8550, Japan

    Contact