SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Clinical trials for SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP) explained in plain language.
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New enzyme pill may take the bite out of root canal pain
Symptom relief Recruiting nowThis study tests whether a tablet called Trinase, made from natural enzymes, can reduce pain after root canal treatment. About 182 men with severe tooth pain will get either Trinase or a placebo before the procedure. Researchers will track their pain levels and how many pain pill…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: Fayoum University • Aim: Symptom relief
Last updated May 17, 2026 10:40 UTC
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New study tests which filling material best saves your painful tooth
Symptom relief Recruiting nowThis study tests two materials, MTA and Biodentine, for treating painful tooth inflammation (irreversible pulpitis) in 60 adults aged 18-40. After removing the infected part of the tooth, one of the materials is placed inside. The goal is to see which material better relieves pai…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: Dow University of Health Sciences • Aim: Symptom relief
Last updated May 17, 2026 10:37 UTC
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Laser zaps toothache pain after Nerve-Saving dental procedure
Symptom relief Recruiting nowThis study looks at children and teens (ages 9-14) with a painful, inflamed nerve in a lower back molar. Instead of a root canal, they will get a pulpotomy, which removes only the infected part of the nerve and seals the tooth. Half will also get a gentle laser treatment on the h…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: University of Fujairah • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Chill out tooth pain: cold therapy may replace extra needles
Symptom relief Recruiting nowThis study looks at whether applying cold inside the mouth (intraoral cryotherapy) can improve numbing for root canal treatment on lower front teeth with severe tooth nerve pain (irreversible pulpitis). About 98 adults with intense tooth pain will receive standard numbing injecti…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: PHASE4 • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated May 06, 2026 16:02 UTC