New enzyme pill may soothe root canal pain

NCT ID NCT07239505

First seen Nov 20, 2025 · Last updated May 02, 2026 · Updated 17 times

Summary

This study tests whether a tablet called Trinase can reduce pain after root canal treatment in people with a painful tooth condition called symptomatic irreversible pulpitis. About 182 men aged 18 to 50 with moderate to severe tooth pain will receive either Trinase or a placebo 30 minutes before the procedure. Researchers will measure pain levels and how many painkillers are needed over 48 hours to see if Trinase helps.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ENDODONTIC DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fayoum University

    RECRUITING

    Al Fayyum, Faiyum Governorate, 12311, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.