SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Clinical trials for SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP) explained in plain language.
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Laser light may help save infected young teeth and speed root growth
Disease control CompletedThis trial tests whether using a low-power laser during a pulpotomy (removing infected pulp from a tooth) can improve healing and root formation in children aged 6 to 14 with painful, irreversible pulpitis in immature permanent molars. Participants receive either laser treatment …
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New laser combo could make toothache treatment less painful for kids
Symptom relief CompletedThis study tests whether using a gentle laser along with a special dental cement can reduce pain after a pulpotomy, a procedure that saves a tooth with a severe nerve infection. About 46 children and young adults aged 9 to 14 with a painful lower molar will be randomly assigned t…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: University of Fujairah • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Ice or steroid? simple rinse could ease root canal pain
Symptom relief CompletedThis study compares two final rinses inside the tooth after root canal treatment for people with severe tooth pain from irreversible pulpitis. One rinse is a cold saline solution (cryotherapy), the other is a steroid solution (dexamethasone). The goal is to see which better reduc…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: PHASE4 • Sponsor: October 6 University • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Dental pain showdown: which filling material hurts less?
Symptom relief CompletedThis study tested three biocompatible materials—TheraCal PT, Biodentin, and MTA—for reducing pain after a pulpotomy (removing the inner pulp) in 51 adults with severe toothache. Participants rated their pain before and up to 7 days after treatment. The goal is to find which mater…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Which bleach solution eases root canal pain better? new study investigates
Symptom relief CompletedThis study looked at 60 adults with painful tooth inflammation (pulpitis) who needed a root canal. Researchers compared two types of sodium hypochlorite (a common disinfectant) — one made for dental use and one household bleach — to see which caused less pain after the procedure.…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Your DNA may determine if the Dentist's needle works
Knowledge-focused CompletedThis study looks at whether certain genetic variations (in COMT, MAOA, and SLC6A4) influence how well a standard dental numbing injection works for people with a painful tooth condition called irreversible pulpitis. Participants received a numbing shot and had their pain levels m…
Matched conditions: SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)
Phase: NA • Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC