SYMPTOMATIC IRREVERSIBLE PULPITIS

This study tests whether a less invasive dental procedure called full pulpotomy can heal infected molars as well as root canals. Researchers will treat 128 adults with deep cavities and compare healing in teeth with and without infection at the root tip. If successful, it may off…

This study tests whether using very cold water (around 2-3°C) to rinse the inside of a tooth during a root canal can lower pain afterward. The trial includes adults aged 20-40 with painful, infected lower molars. Participants are randomly assigned to receive either cold rinses th…

This study looks at whether using a cold saline rinse after ultrasonic cleaning during a root canal can lower pain afterward. Adults with an inflamed tooth nerve will get either ultrasonic cleaning alone or followed by a cold saline flush. Pain levels are tracked for three days a…

This study compares two ways of using an anti-inflammatory drug (ketorolac) during root canal treatment: one at room temperature and one chilled. The goal is to see if the cold version reduces pain better after the procedure. Sixty adults with tooth infections will be enrolled, a…

This study compares two ways of applying cold inside a tooth during a root canal to see which reduces pain better. Ninety adults with a painful, inflamed tooth nerve will be randomly assigned to receive either ice sticks, a cold spray, or no extra cold treatment. Patients will ra…

This study compares two types of dental sealers used after root canal treatment to see which causes less pain. About 118 adults with painful tooth inflammation will receive either a tricalcium silicate sealer or a resin-based sealer. Pain levels will be measured at 24 hours, 72 h…

This study tests whether using a dental operating microscope during a pulpotomy (a partial root canal) reduces pain and improves quality of life afterward. 82 adults with deep cavities and tooth nerve pain will be randomly assigned to get the procedure with or without the microsc…

This study compares two single-dose pain relievers—piroxicam and prednisolone—given before a root canal to see which one reduces pain better afterward. Sixty adults with an inflamed tooth nerve and infection will take one of the drugs right before treatment. The goal is to find a…

This study compares two ways to manage pain after a root canal. One group gets ibuprofen alone, the other gets ibuprofen plus alprazolam, a medicine that reduces anxiety. 110 adults with tooth pain will rate their pain over 24 hours. The goal is to see if adding alprazolam leads …