Chilled painkiller could cool down Post-Root-Canal pain

NCT ID NCT06584188

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways of using an anti-inflammatory drug (ketorolac) during root canal treatment: one at room temperature and one chilled. The goal is to see if the cold version reduces pain better after the procedure. Sixty adults with tooth infections will be enrolled, and pain levels will be measured using a standard pain scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketorolac tromethamine

What this could lead to

If it works, this could offer a better way to manage pain after root canal treatment.

What could go wrong

This is a small, early Phase 2 trial. The cold version may not work better than the room-temperature version, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative periapical periodontitis pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Ain Shams University

    Cairo, Egypt