STAGE IIIB LUNG CANCER AJCC V8
Clinical trials for STAGE IIIB LUNG CANCER AJCC V8 explained in plain language.
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New combo therapy aims to keep lung cancer from returning after surgery
Disease control Recruiting nowThis phase 3 trial tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy after surgery can help prevent non-small cell lung cancer from coming back. About 1,210 people with stage II to IIIB lung cancer will receive either chemo plus pembrolizumab toge…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 02:00 UTC
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Could an immune booster keep early lung cancer from returning?
Disease control Recruiting nowThis phase 3 trial is testing whether the immunotherapy drug durvalumab, given after surgery, can prevent early-stage non-small cell lung cancer from coming back. About 306 participants who have had their tumor completely removed will be randomly assigned to receive durvalumab or…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 02:00 UTC
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New trial aims to find best treatment for older lung cancer patients
Disease control Recruiting nowThis phase III trial compares adding chemotherapy to immunotherapy (pembrolizumab) versus immunotherapy alone in adults aged 70+ with advanced non-small cell lung cancer. The goal is to see if the combination improves survival. About 304 participants will be enrolled.
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 02:00 UTC
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New combo aims to outsmart lung Cancer's growth signals
Disease control Recruiting nowThis Phase III trial is testing whether adding bevacizumab to the standard drug osimertinib can better control advanced EGFR-mutant non-small cell lung cancer. About 300 people with stage IIIB or IV disease will be randomly assigned to receive either the combination or osimertini…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could a muscle relaxant help fight lung cancer? scientists test papaverine with standard therapy
Disease control Recruiting nowThis trial investigates whether adding papaverine—a drug traditionally used as a muscle relaxant—to standard chemoradiation can improve treatment for people with stage II to III non-small cell lung cancer. Papaverine targets the energy factories inside cancer cells (mitochondria)…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, given alone or with the immunotherapy drug pembrolizumab. The goal is to see if the combination is safe and helps the immune system attack advanced solid tumors. About 132 people with various advanc…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Lung cancer trial tests whether chemo before surgery boosts survival
Disease control Recruiting nowThis phase III trial is testing whether giving chemotherapy and immunotherapy both before and after surgery (perioperative) is better than giving it only after surgery (adjuvant) for people with stage II-IIIB non-small cell lung cancer that can be removed. About 1,100 participant…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New drug combo aims to shrink lung tumors before surgery
Disease control Recruiting nowThis phase II trial is testing whether giving a combination of two immunotherapy drugs (cemiplimab and fianlimab) before surgery can kill more tumor cells in people with stage IB to IIIB non-small cell lung cancer. About 60 participants will receive the drugs intravenously, then …
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New combo aims to control lung cancer that returns after standard therapy
Disease control Recruiting nowThis phase II trial tests whether adding local treatments like surgery or radiation to the immunotherapy drug durvalumab can help control stage III non-small cell lung cancer that has progressed after chemoradiation and durvalumab. About 51 participants with 3 or more growing tum…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Can a drug stop lung cancer before it starts? new trial aims to find out
Prevention Recruiting nowThis study tests whether the drug canakinumab can prevent lung cancer in 50 people who have suspicious lung nodules that haven't gone away. Participants receive the drug and are monitored for nodule shrinkage and cancer development. The goal is to see if this approach can stop lu…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 13:08 UTC
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Simple breathing workouts before lung surgery may cut pneumonia risk
Symptom relief Recruiting nowThis phase 2 trial tests whether doing special breathing exercises (respiratory muscle training) for a few weeks before lung cancer surgery can reduce serious lung complications like pneumonia and breathing trouble. About 220 people with stage I-IIIB lung cancer will either do th…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Can yoga ease cancer Treatment's toll on patients and families?
Symptom relief Recruiting nowThis study tests whether a yoga program designed for both patients and their family caregivers can improve physical function, fatigue, sleep, mood, and quality of life. It includes 400 people with lung or esophageal cancer who are getting radiation therapy, plus their caregivers.…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Blood tests may guide better lung cancer treatment choices
Knowledge-focused Recruiting nowThis study looks at blood and tissue samples from people with advanced non-small cell lung cancer to find markers that predict how well immunotherapy works. The goal is to use these markers to choose the best second-line treatment if the first one stops working. About 535 partici…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Could a poop transplant fix cancer treatment side effects?
Knowledge-focused Recruiting nowThis study looks at how the bacteria in your gut might cause stomach issues like diarrhea and colitis when you take certain cancer drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or g…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Can personalized chemoradiation protect lung cancer Patients' hearts?
Knowledge-focused Recruiting nowThis study looks at how chemoradiation for locally advanced lung cancer affects the heart. Researchers will track 100 patients using heart tests, blood samples, and questionnaires. The goal is to see if tailoring treatment based on individual risk can reduce heart problems.
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC