STAGE IIIB LUNG CANCER AJCC V8
Clinical trials for STAGE IIIB LUNG CANCER AJCC V8 explained in plain language.
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New attack on stubborn lung cancer: zap tumors, then boost immunity
Disease control Recruiting nowThis study is for people with stage III non-small cell lung cancer that has started to grow again (progressed) after their initial chemo-radiation and immunotherapy. It tests whether using targeted treatments like surgery or radiation to attack specific progressing tumors, follow…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Smart radiation adjustments aim to protect Patients' hearts and lungs
Disease control Recruiting nowThis study is testing whether updating radiation treatment plans at set times during therapy can reduce damage to healthy heart and lung tissue in people with non-small cell lung cancer. Researchers want to see if this adaptive approach lowers side effects like lung inflammation …
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Can a year of treatment stop lung cancer from coming back?
Disease control Recruiting nowThis study is for people with early-stage non-small cell lung cancer who have had surgery and whose initial treatment completely removed the cancer. It compares two approaches: one group receives a year of immunotherapy (durvalumab) to try to prevent the cancer from returning, wh…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Two drugs vs. one: major trial aims to extend life for advanced lung cancer patients
Disease control Recruiting nowThis study is for people with a specific type of advanced lung cancer that has spread and has an EGFR gene change. It compares a standard drug (osimertinib) alone against that same drug combined with a second drug (bevacizumab). The goal is to see if the two-drug combination can …
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Double-Punch immune therapy trial aims to wipe out lung cancer before surgery
Disease control Recruiting nowThis study is testing whether giving two immunotherapy drugs before surgery can help the body's immune system attack and shrink early-stage non-small cell lung cancer. The goal is to kill more cancer cells before the tumor is removed, potentially leading to better long-term resul…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Major trial aims to stop lung Cancer's return after surgery
Disease control Recruiting nowThis large, late-stage trial is testing if adding an immunotherapy drug (pembrolizumab) to standard chemotherapy helps patients live longer without their cancer returning. It is for people with stage II or III non-small cell lung cancer who have already had their tumor surgically…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Double-Duty treatment trial aims to extend lives of vulnerable seniors with lung cancer
Disease control Recruiting nowThis study is for adults 70 and older with advanced non-small cell lung cancer. It compares two treatment approaches: immunotherapy alone versus immunotherapy combined with chemotherapy. The main goal is to see if the combination helps patients live longer and better control thei…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Major trial tests if timing of cancer drugs around surgery improves survival
Disease control Recruiting nowThis large study aims to find the best timing for cancer treatments in people with operable non-small cell lung cancer. It will compare the standard approach of giving chemotherapy and immunotherapy only after surgery to a newer approach of giving it both before and after surgery…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 11, 2026 14:54 UTC
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Drug trial aims to stop lung cancer before it starts
Prevention Recruiting nowThis study is testing if a drug called canakinumab can prevent lung cancer in people who have suspicious, high-risk spots (nodules) in their lungs. About 50 participants will receive injections of the drug every 3 weeks for up to 8 cycles. The main goal is to see if the drug can …
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Could simple breathing exercises before surgery prevent dangerous complications?
Prevention Recruiting nowThis study is testing whether a special breathing exercise program before lung cancer surgery can help prevent serious lung problems like pneumonia after the operation. It involves 220 patients with early to mid-stage lung cancer. Half will do breathing muscle training with a dev…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Prevention
Last updated Mar 25, 2026 14:09 UTC
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Yoga study aims to ease cancer treatment burden for patients and families
Symptom relief Recruiting nowThis study is testing whether a yoga program for patients and their caregivers can improve physical function and quality of life during radiation treatment for lung or esophageal cancer. It will compare yoga sessions to educational sessions to see which helps patients walk farthe…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Tracking heart damage in lung cancer treatment: can personalized plans protect patients?
Knowledge-focused Recruiting nowThis study aims to understand how radiation and chemotherapy for advanced lung cancer affects heart health over time. Researchers will follow 100 patients receiving personalized treatment plans, measuring heart fitness and injury markers before, during, and for years after treatm…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Could poop transplants ease cancer drug side effects?
Knowledge-focused Recruiting nowThis study aims to understand why some cancer patients develop severe diarrhea and colon inflammation (colitis) while taking powerful immunotherapy drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 patients with melanoma…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 05, 2026 14:00 UTC