STAGE III PROSTATE CANCER AJCC V8
Clinical trials for STAGE III PROSTATE CANCER AJCC V8 explained in plain language.
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New proton beam therapy aims to cut side effects in prostate cancer treatment
Disease control Recruiting nowThis study tests a precise type of radiation called proton therapy for men with high-risk prostate cancer that has spread to lymph nodes. The goal is to see if targeting the tumor and nearby lymph nodes with protons causes fewer bowel and urinary side effects than standard radiat…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Emory University • Aim: Disease control
Last updated Jun 17, 2026 02:57 UTC
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New drug combo may delay prostate cancer spread in High-Risk patients
Disease control Recruiting nowThis study tests whether adding the drug apalutamide to standard hormone therapy and radiation helps men with prostate cancer that has spread to lymph nodes after surgery. About 586 participants will receive either the usual treatment or the usual treatment plus apalutamide. The …
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 17, 2026 02:54 UTC
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Could a new pill help men with aggressive prostate cancer stay Cancer-Free longer?
Disease control Recruiting nowThis study is for men with high-risk prostate cancer that hasn't spread far. It tests whether adding the drug niraparib to standard hormone therapy after radiation can keep the cancer from coming back longer. About 200 men will take part, and researchers will track cancer progres…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 12:50 UTC
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Heart-Safe prostate cancer treatment? new trial compares two hormone drug combos
Disease control Recruiting nowThis study compares two different hormone therapy combinations for men with advanced prostate cancer who are also getting radiation. The goal is to see which combination causes less harm to the heart. About 72 men will take either leuprolide plus abiraterone acetate or relugolix …
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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Five shots instead of forty: prostate cancer radiation trial aims to cut treatment time
Disease control Recruiting nowThis study compares a new, shorter radiation method (5 treatments over 2 weeks) to the usual longer course (20-45 treatments over 4-9 weeks) for men with high-risk prostate cancer. The goal is to see if the shorter schedule works just as well at preventing the cancer from spreadi…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Testosterone therapy for prostate cancer patients: a Game-Changer for quality of life?
Disease control Recruiting nowThis study looks at whether testosterone replacement therapy (TRT) is safe and beneficial for men with low-risk prostate cancer who are on active surveillance (watchful waiting). Many doctors avoid TRT in these patients due to fear it might make the cancer grow. The trial will tr…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE4 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New nerve wrap could help men recover faster after prostate cancer surgery
Disease control Recruiting nowThis study tests a special tissue wrap placed on nerves during prostate removal surgery to see if it helps men recover erectile and bladder control faster. About 25 men with localized prostate cancer will take part. The wrap acts as a protective barrier, and researchers will chec…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 11, 2026 12:11 UTC
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Vitamin d may shield bones in men on prostate cancer treatment
Disease control Recruiting nowThis study tests whether high-dose vitamin D can prevent bone loss in men aged 50+ with prostate cancer who are receiving hormone therapy (ADT). ADT can weaken bones, raising the risk of fractures. Researchers will give 240 participants either high-dose vitamin D or a placebo for…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: University of Rochester • Aim: Disease control
Last updated Jun 11, 2026 11:57 UTC
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Hormone boost may sharpen prostate cancer scans
Diagnosis Recruiting nowThis study tests whether a short course of hormone therapy (relugolix) can make PSMA PET/CT scans better at finding prostate cancer that has spread to lymph nodes. About 30 men with high-risk prostate cancer will get the hormone drug for 5, 10, or 15 days before their scan. The g…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 15, 2026 19:02 UTC
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New scan may spare prostate cancer patients from unnecessary surgery
Diagnosis Recruiting nowThis study tests whether a new type of PET/MRI scan can accurately detect if prostate cancer has spread to nearby lymph nodes. About 50 men with high-risk prostate cancer who are scheduled for prostate removal surgery will receive the scan beforehand. The goal is to see if the sc…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 12, 2026 12:03 UTC
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New radiation technique aims to cut prostate cancer treatment side effects
Symptom relief Recruiting nowThis study tests a new way to deliver radiation for prostate cancer that hasn't spread. By using real-time motion tracking during treatment, doctors hope to target the tumor more precisely and reduce common side effects like urinary and bowel problems. About 80 men with early-sta…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 16, 2026 12:55 UTC
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Home cancer care trial aims to ease burden for black men with prostate cancer
Symptom relief Recruiting nowThis study looks at whether giving cancer therapy at home instead of in a clinic is safe and improves the experience for Black men with advanced prostate cancer. About 38 participants will receive treatment both at home and in the clinic, then rate their satisfaction and report s…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 16, 2026 12:54 UTC
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Which prostate cancer drug is easier on patients? new study aims to find out
Symptom relief Recruiting nowThis study compares the side effects of two standard treatments for advanced prostate cancer: abiraterone plus prednisone versus darolutamide alone. Researchers want to see which drug causes fewer severe side effects in 75 adult patients. The goal is to help doctors choose the tr…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jun 16, 2026 12:49 UTC
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Smart radiation adjusts daily to spare bladder in prostate cancer
Symptom relief Recruiting nowThis study tests a smarter way to deliver radiation for prostate cancer that hasn't spread. Instead of using a fixed plan, doctors adjust the radiation each day based on real-time images of the prostate and bladder. The goal is to see if this approach lowers urinary side effects …
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 12, 2026 12:08 UTC
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Shining a light on cancer fatigue: new study tests bright light therapy for men on hormone treatment
Symptom relief Recruiting nowThis study tests if using bright white light therapy can reduce fatigue and improve mood in men with advanced prostate cancer who are receiving hormone therapy (ADT) combined with other treatments. About 210 men will either start light therapy right away or after a delay. The goa…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 11, 2026 11:57 UTC
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Teeing up for better health: golf program aims to boost survivorship in prostate cancer patients
Symptom relief Recruiting nowThis study tests whether a supervised golf exercise program can help prostate cancer survivors who are on hormone therapy improve their physical function, balance, thinking skills, and quality of life. Twenty men aged 55-85 with no or little golf experience will take part. The pr…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 01, 2026 17:55 UTC