STAGE II PROSTATE CANCER AJCC V8
Clinical trials for STAGE II PROSTATE CANCER AJCC V8 explained in plain language.
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Study challenges old fear: giving testosterone to men with prostate cancer
Disease control TerminatedThis study is testing if giving testosterone replacement therapy (TRT) to men with low testosterone and early-stage prostate cancer is safe and improves their quality of life. The men are on 'active surveillance,' which means their cancer is being closely monitored instead of bei…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: PHASE4 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Shorter radiation course tested for prostate cancer recovery
Disease control OngoingThis study compares two radiation schedules given after prostate cancer surgery. It tests whether a shorter, more intense 4.5-week course works as well as the standard 7-week course at keeping cancer from returning. Researchers will track side effects and quality of life for up t…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Trial tests Immune-Boosting drug to wipe out prostate cancer
Disease control TerminatedThis study aimed to see if adding the immunotherapy drug pembrolizumab to standard hormone therapy and radiation could better eliminate cancer in men with high-risk prostate cancer that hasn't spread. The main goal was to check if a follow-up biopsy showed no cancer after treatme…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Prostate cancer radiation showdown: which method spares Patients' daily lives?
Disease control OngoingThis study is comparing two different ways to deliver targeted radiation to treat early-stage prostate cancer that hasn't spread. One method places a temporary radioactive seed inside the prostate; the other uses precise external beams over five sessions. The main goal is to see …
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 23, 2026 15:28 UTC
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Gentler dose tested to control prostate cancer before surgery
Disease control OngoingThis study is testing if a very low dose of the drug apalutamide can help control prostate cancer before surgery. It involves men whose cancer is still confined to the prostate gland. The main goal is to see if this short, low-dose treatment can effectively lower PSA levels, a ke…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Phone coaching aims to ease the wait for prostate cancer patients
Symptom relief OngoingThis study is testing a lifestyle support program called 'Watchful Living' for Black and Hispanic men with early-stage prostate cancer who are on active surveillance (watching and waiting) and their partners. The program provides phone coaching on exercise and nutrition over six …
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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New surgical technique aims to stop leaks after prostate removal
Symptom relief TerminatedThis study compares two versions of robotic prostate cancer surgery to see if adding a bladder-supporting stitch helps men regain bladder control faster. About 200 men with early-stage prostate cancer will be randomly assigned to receive the standard surgery or the surgery with t…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Mar 27, 2026 12:37 UTC
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Partner power: can couples team up to fight Cancer's aftermath?
Symptom relief OngoingThis study is testing a lifestyle program designed for African American men who have finished treatment for prostate cancer and their spouses or partners. The goal is to see if working together as a couple can help improve quality of life, increase physical activity, and encourag…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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Can a mediterranean diet change prostate cancer biology before surgery?
Knowledge-focused OngoingThis study is testing whether it's practical for men with intermediate-risk prostate cancer to follow a strict Mediterranean diet for four weeks before their scheduled surgery. The main goal is to see if patients can stick to the diet and to measure how it affects their body chem…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Prostate cancer hormone Therapy's hidden heart risk: new study seeks answers
Knowledge-focused OngoingThis study aims to understand how certain prostate cancer hormone treatments affect heart health. It will compare two different hormone drugs given alongside radiation therapy to see which might be safer for the heart. Researchers will use heart scans and blood tests to learn why…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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DNA test aims to predict painful side effects of prostate cancer radiation
Knowledge-focused OngoingThis study is testing whether a genetic test can predict which prostate cancer patients are at high or low risk for serious urinary and bowel side effects from a specific type of radiation therapy. About 208 men with early-stage prostate cancer will take the test, and then discus…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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How couples cope: tracking stress and health after prostate cancer
Knowledge-focused OngoingThis study aims to understand the daily ups and downs of stress, social support, and healthy habits like exercise and diet in Black men who have survived prostate cancer and their partners. Researchers are observing how couples cope with stress together and how that affects their…
Matched conditions: STAGE II PROSTATE CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC