Aspirin and immune boosters could help fight prostate cancer before surgery
NCT ID NCT03899987
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether giving a combination of enteric-coated aspirin, rintatolimod, and interferon-alpha 2b before prostate cancer surgery can boost the immune system's attack on tumors. The study involves 12 men with localized prostate cancer who are scheduled for surgery. The main goal is to see if these drugs increase cancer-fighting immune cells in the tumor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- enteric-coated aspirin, rintatolimod, and interferon-alpha 2b
- What this could lead to
- If successful, this could point toward a new pre-surgery treatment that helps the immune system fight prostate cancer and lowers the chance of it coming back.
- What could go wrong
- This is a very small early-phase trial with only 12 participants, so results may not apply broadly. The drugs may cause side effects like flu-like symptoms or bleeding risks from aspirin.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can surgery boost control of spread prostate cancer?
- Can a better scan sharpen radiation for prostate cancer?
- Hormone therapy showdown: can an oral pill beat the shot for prostate cancer patients?
- Can tracking tumor movement during radiation make treatment more precise?
- Can a single small incision preserve sexual function after prostate cancer surgery?
- Can a shorter course of radiation tame prostate cancer with fewer side effects?