SOLID TUMOR CANCER

This study is testing a new combination of two drugs, IN10018 and RNK08954, for people with advanced solid tumors that have a specific genetic change called KRASG12D. The main goals are to find a safe and effective dose and to see if the treatment can shrink tumors. The study is …

This is the first-ever study in people for a new experimental drug called AVZO-103. It aims to find a safe and effective dose for adults with advanced cancers that have spread, including bladder cancer. The study will test the drug alone and in combination with other therapies to…

This study is testing a new drug called GV20-0251 for adults with advanced solid tumor cancers that have progressed despite standard treatments. The first part aims to find a safe dose, and the second part will see how well the drug works against several types of cancer, includin…

This is a first-in-human study to test a new investigational drug called SYS6043 in adults with advanced or metastatic solid tumors that have spread or no longer respond to standard therapies. The main goals are to find a safe dose, understand the drug's side effects, and see how…

This study is testing a new combination of two immunotherapy drugs, HLX43 and serplulimab, for people with advanced solid tumors or a specific type of lung cancer. The main goals are to find a safe and effective dose and to see if the treatment can shrink tumors. It will enroll a…

This study is testing whether restricting eating to an 8-hour daily window during cancer treatment improves outcomes and reduces side effects. It will enroll 100 Alaska Native patients with rectal or breast cancer who are receiving standard treatment. Researchers will compare tho…

This is the first human study of an experimental cancer drug called PLT012. Researchers want to find the safest dose for adults with advanced solid tumors and see if it shows early signs of helping. All 36 participants will receive the drug through an IV every three weeks while d…

This is a very early study to check the safety and initial signs of effectiveness of a new drug called WTX212A. It will be given to 12 adults with advanced solid tumors, either by itself or combined with radiation therapy. The main goals are to see if the treatment is safe and ho…

This is the first human trial testing a new cancer drug called AVZO-1418. Researchers want to find the safest dose and see if it can shrink tumors in adults with advanced solid cancers that have spread or cannot be removed by surgery. The study will test the drug alone and possib…

This early-stage study is testing a new cell therapy called TC-G203 for people with advanced solid tumors that have returned or spread. The main goal is to find the safest dose and see how well the body handles the treatment. It is for patients whose cancer has a specific marker …

This study is testing a new, personalized approach to treat advanced cancers that are no longer responding to standard therapies. Doctors will take a small sample of a patient's tumor and grow it in a lab to create a 'mini-tumor' model. They will then test many different cancer d…

This study is testing a new diagnostic platform that uses artificial intelligence to analyze small pieces of a patient's tumor. The goal is to predict whether a patient's cancer will respond to immunotherapy drugs before they start treatment. Researchers will compare the AI's pre…

This study is testing whether a new smartphone app can help people better manage the side effects of chemotherapy. The app combines daily symptom check-ins with data from a Fitbit activity tracker. If the app detects concerning symptoms or health readings, it suggests when to con…

This study aims to better understand and classify solid tumors by analyzing specific chemical changes in tumor DNA, called methylation patterns. Researchers will collect and analyze tumor tissue samples from 180 patients with brain, endometrial, or endocrine cancers. The goal is …

This study is testing a blood test that looks for tiny pieces of tumor DNA to see if it can detect cancer recurrence earlier than standard scans. It aims to enroll 100 adults, including people with various solid tumors and healthy volunteers. The goal is to gather information tha…

This study is testing a program to screen cancer patients for emotional distress and connect those who need help with mental health services. It involves 50 English- or Spanish-speaking adults with a new solid tumor cancer diagnosis at a specific NYC hospital. The goal is to see …