SMALL CELL LUNG CARCINOMA

This study is testing whether people with a specific type of lung cancer can be safely monitored at home after receiving a new drug treatment, instead of staying in the hospital. Researchers want to see if a 'Hospital-at-Home' program using telehealth is a more efficient way to w…

This study is testing whether a precise, high-dose radiation treatment called stereotactic radiosurgery (SRS) can help people with small cell lung cancer that has spread to the brain. It will measure how many participants are still alive 6 months after receiving the treatment. Th…

This is an early-stage study to test the safety and find the right dose of a new radioactive drug called [225Ac]Ac-ETN029 for adults with advanced cancers that have a protein called DLL3. The trial will also test an imaging version of the drug to see where it goes in the body. Re…

This is the first human trial of a new experimental cancer drug called LY4175408. It is designed to target and deliver a toxic payload specifically to cancer cells that have a certain marker (PTK7). The study will test the drug's safety, side effects, and early signs of effective…

This study is testing a new oral drug, PC14586 (rezatapopt), for people with advanced solid tumors that have a specific mutation in a gene called TP53 (Y220C). The main goals are to find a safe and effective dose and to see if the drug can shrink tumors. The trial is enrolling up…

This early study is testing the safety of a new cell therapy for adults with advanced lung cancer that has stopped responding to standard treatments. Doctors will collect a patient's own immune cells, modify them in a lab to better target cancer, and then infuse them back into th…

This study is testing the safety and effectiveness of the immunotherapy drug durvalumab for people in Spain with a specific, aggressive type of lung cancer called limited-stage small cell lung cancer. The drug is given after patients have completed standard chemotherapy and radia…

This study is testing whether a drug called onvansertib can help people with small cell lung cancer that has returned after chemotherapy. Researchers will give the drug to 37 patients who have already tried one or two chemotherapy treatments. They want to see if the drug shrinks …

This study is testing whether adding a new drug called cirtuvivint to standard chemotherapy can better control small cell lung cancer that has returned after initial treatment. It will enroll about 42 adults whose cancer has progressed after prior platinum-based chemotherapy. The…

This is the first study in people to test a new oral drug called NKT3964. It aims to see if the drug is safe and can help control advanced cancers that have spread and stopped responding to standard treatments. The study will enroll adults with specific advanced solid tumors, inc…

This study is testing several new experimental drugs, alone or combined with an existing immunotherapy (pembrolizumab), for people with an aggressive form of lung cancer. It is for patients whose cancer has continued to grow despite their first treatment, which included a similar…

This study is testing a new drug called BI 764532 for adults with advanced small cell lung cancer or other neuroendocrine cancers that have returned or stopped responding to standard treatments. The main goals are to find a safe and effective dose and to see if the drug can shrin…

This early-stage trial is testing the safety and dosing of an experimental drug called PF-08046050 in adults with advanced solid tumors that have returned or stopped responding to standard treatments. The drug is designed to attach to cancer cells and deliver a toxic payload dire…

This study is testing a new type of imaging scan to see if it can safely and effectively detect small cell lung cancer and similar tumors. The scan uses a special tracer that attaches to a protein called DLL3, which is often found on these cancer cells. Researchers want to see if…

This study aims to understand why some people develop lung cancer at age 45 or younger, which is unusual. Researchers will collect blood, saliva, and tumor samples from 500 participants to look for genetic patterns and risk factors. The goal is to gather knowledge that could lead…

This study aims to collect long-term health information and blood/tissue samples from 730 lung cancer patients treated at Nantes University Hospital. By tracking patients from diagnosis through their entire treatment journey, researchers hope to understand how treatments work in …