SLEEP APNEA, OBSTRUCTIVE

This study follows 20 people with obstructive sleep apnea who are already using a special nasal airway device. Researchers will check in with participants and have them fill out sleep questionnaires after 12 months. The goal is to see how well the device works over time and if it…

This study tests a new device placed in the nose (NPA-OSA) to help adults with moderate to severe obstructive sleep apnea who cannot tolerate CPAP machines. Over 30 days, 20 participants will use the device at home to see if it reduces breathing pauses during sleep. The goal is t…

This study looks at whether using a CPAP machine at night can help lower high red blood cell levels (polycythemia) in people with moderate to severe sleep apnea. About 182 adults will be randomly assigned to use CPAP or not, and their blood will be checked over 12 months. The goa…

This study tests whether a custom mouthpiece (mandibular advancement device) can help control sleep apnea symptoms and protect heart health when people temporarily stop using their CPAP machine. About 40 adults who have used CPAP for over a year will be enrolled. The goal is to f…

This study tests whether a specific jaw surgery can improve breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot use standard treatments like CPAP machines. About 48 adults will be followed over time to see if the surgery reduces sleep apnea…

This study is testing a new tool that measures how sensitive the throat is to help diagnose obstructive sleep apnea (OSA). About 117 adults with suspected OSA will take part. The goal is to see if this simple, quick test can accurately identify the condition, potentially offering…

This study tests a once-weekly medicine called eloralintide in 800 adults with moderate-to-severe sleep apnea who are also overweight or have obesity. The goal is to see if it can improve breathing during sleep and help with weight loss. Some participants use a CPAP machine, whil…

This study tests whether adding a small extra step (lateral pharyngoplasty) to standard tonsil removal helps children ages 3-17 recover better. Researchers will compare pain levels, how soon kids can eat and drink normally, and the risk of bleeding after surgery. The goal is to f…

This study follows 82 children aged 8–18 who are starting positive airway pressure (PAP) therapy for obstructive sleep apnea. Researchers want to see if insomnia makes it harder for kids to use their PAP machine regularly, and whether race or ethnicity plays a role. The goal is t…

This study looks at how obstructive sleep apnea (pauses in breathing during sleep) affects blood sugar levels in adults with type 1 diabetes. Researchers will monitor 40 participants' glucose patterns using continuous glucose monitors. The goal is to understand if sleep apnea mak…

This study looks at whether breathing through the nose or mouth changes how the airway collapses during a special sleep endoscopy test. Researchers will study 50 adults with sleep apnea to see if the breathing route during the test matches natural sleep. The goal is to improve ho…

This study looks at whether measuring how the airway opens during a sleep exam can predict if a nerve stimulator (Inspire) will work for people with obstructive sleep apnea who cannot use CPAP. About 60 adults with moderate to severe sleep apnea will take part. Researchers will s…

This study tests a program called REPOSE, where a patient navigator helps families overcome barriers to get their child with sleep-disordered breathing (like sleep apnea) to a specialist. About 80 parents of children aged 2 to 12 will be enrolled. The goal is to see if this suppo…