New study aims to end guesswork in sleep apnea implant success
NCT ID NCT05429983
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 60 people with moderate to severe sleep apnea who are being evaluated for a nerve stimulator implant (Inspire). During a routine sleep endoscopy, researchers will measure how the airway responds to direct muscle stimulation. They want to see if these measurements can predict who will have a good response to the implant, defined as a 50% reduction in apnea events. The goal is to improve patient selection and avoid implanting the device in people who won't benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hypoglossal nerve stimulation device (Inspire)
What this could lead to
If successful, this could help doctors better predict which sleep apnea patients will benefit from the Inspire device, reducing the number of people who get the implant but don't improve.
What could go wrong
This is an early-stage observational study with only 60 participants. The measurements may not reliably predict outcomes, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••