New study aims to end guesswork in sleep apnea implant success
NCT ID NCT05429983
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looks at 60 people with moderate to severe sleep apnea who are being evaluated for a nerve stimulator implant (Inspire). During a routine sleep endoscopy, researchers will measure how the airway responds to direct muscle stimulation. They want to see if these measurements can predict who will have a good response to the implant, defined as a 50% reduction in apnea events. The goal is to improve patient selection and avoid implanting the device in people who won't benefit.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- hypoglossal nerve stimulation device (Inspire)
- What this could lead to
- If successful, this could help doctors better predict which sleep apnea patients will benefit from the Inspire device, reducing the number of people who get the implant but don't improve.
- What could go wrong
- This is an early-stage observational study with only 60 participants. The measurements may not reliably predict outcomes, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SLEEP APNEA, OBSTRUCTIVE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new pressure relief mode outperform standard therapy for sleep apnea?
- Freezing away sleep apnea: a new procedure targets throat fat to open the airway
- Your smartwatch could spot sleep apnea: study tests At-Home screening
- Camera during sleep may reveal best surgery for apnea
- Personalized sleep apnea treatment on the horizon?
- Tiny electrode zaps tongue nerve to fight sleep apnea