SJOGREN'S SYNDROME

This Phase 2 study tested an experimental drug called SAR441344 in 84 adults with primary Sjögren's syndrome, a condition causing dry eyes, dry mouth, and fatigue. Participants received either the drug or a placebo by injection over 12 weeks. The goal was to see if the drug could…

This study tested whether baricitinib, a drug that calms the immune system, can help people with active Sjogren's syndrome. About 87 adults were randomly assigned to take either hydroxychloroquine alone or baricitinib with or without hydroxychloroquine for 24 weeks. The goal was …

This study looked at the safety of a drug called iscalimab in 206 people with Sjögren's syndrome, a condition that causes dry eyes and mouth. Participants had already been in an earlier study and continued to receive the drug. The goal was to see if iscalimab is safe and to check…

This study tested an experimental drug called nipocalimab in 163 adults with primary Sjogren's syndrome, an autoimmune disease causing dryness and fatigue. Participants received either the drug or a placebo for 24 weeks. The goal was to see if nipocalimab could reduce overall dis…

This study tested an artificial intelligence (AI) program designed to help doctors diagnose Sjogren's syndrome. The AI analyzed images of minor salivary gland biopsies from 1,000 people with suspected Sjogren's. The goal was to see if the AI could count immune cells as accurately…

This small pilot study tested whether a wheat-free and cow's milk-free diet could reduce symptoms in people with Sjogren's disease, an autoimmune condition causing dryness, pain, and fatigue. Thirty participants were randomly assigned to either the special diet or a control diet …

This study looked at whether regular aerobic exercise, like walking, can reduce fatigue in women with primary Sjögren's syndrome. Forty-five women participated in a 16-week program. Researchers measured changes in fatigue, mood, and physical fitness.

This small study tested whether levocarnitine, a natural substance, can help treat dry eye in adults with Sjogren's syndrome. Fifteen participants received both the drug and a placebo in a crossover design. The goal was to see if levocarnitine reduces eye inflammation and improve…

This study examined whether women with autoimmune diseases or inflammatory rheumatism receive proper gynecological follow-up, including cervical cancer screening and contraception advice. Researchers surveyed 318 women with conditions like lupus, rheumatoid arthritis, and Sjögren…

This study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers asked 151 patients about 10 different digestive symptoms using a simple questionnaire. The goal was to understand which symptoms are most common and how they relate to how lon…

This study looked at whether immune cells from the intestine play a role in Sjogren's syndrome, an autoimmune disease that causes dry eyes and mouth. Researchers examined saliva gland samples from 57 adults suspected of having Sjogren's. The goal was to better understand the dise…

This study looked at 100 people with primary Sjögren's syndrome to understand how the disease affects their physical, emotional, and social well-being. Researchers used questionnaires and simple tests to measure symptoms like fatigue, pain, swallowing problems, and mood. A health…