SEXUALLY TRANSMITTED DISEASES

This study tested an experimental gonorrhea vaccine in healthy adults aged 18 to 50. The goal was to see if the vaccine is safe and can prevent gonorrhea infections. Over 1,000 participants received either the vaccine or a placebo (salt water shot) and were monitored for side eff…

This trial tests a community-based approach to HIV prevention for young people aged 15-30 in rural KwaZulu-Natal, South Africa. Peer navigators guide participants to mobile clinics that offer sexual health services, including HIV testing, PrEP, and contraception. The goal is to r…

This study tested whether kudzu, an herbal supplement, can help people who binge drink reduce their alcohol use and related risky sexual behaviors. Researchers enrolled 120 sexually active adults who binge drink and are at high risk for HIV. Participants received either kudzu or …

This study tested a new synthetic nitrile condom against a standard latex condom in 305 couples. Each couple used both types five times to see how often they broke or slipped. The goal was to see if the new condom works as well as latex for preventing sexually transmitted disease…

This study evaluates a disposable, at-home PCR test that detects chlamydia and gonorrhea from a urine sample. Men aged 14 and older collect their own sample and use the test with app or written instructions. The goal is to see if the test works accurately outside a clinic, potent…

This study tested a strategy of using rapid, point-of-care diagnostic tests for sexually transmitted infections (STIs) in pregnant women attending antenatal clinics in Zimbabwe. Over 1,000 women were offered testing for chlamydia, gonorrhea, trichomoniasis, syphilis, and hepatiti…

This trial tests a tablet-based decision support tool designed to help women learn about their HIV risk and prevention options, including PrEP. Women aged 18-45 who are not living with HIV will be randomly assigned to use the tool before a clinic visit or to receive standard coun…

This study tested whether a program designed specifically for women who use drugs could help them reduce their risk of HIV and other sexually transmitted diseases. 501 women were randomly assigned to receive either standard counseling, standard counseling plus a well-woman exam, …

This study tested a tablet-based tool and clinic training to help women learn about HIV prevention, including PrEP. 141 women from a Florida clinic participated. The goal was to see if these tools helped women make informed choices and start prevention methods.

This study tested an online program called itMatters designed to reduce sexually transmitted infections (STIs) among college students. The program focuses on the link between drinking alcohol and risky sexual behavior, such as not using condoms. Over 3,000 first-year students fro…

This completed trial tested a digital program called LuvHub for male couples. The program includes modules on HIV/STI prevention, communication, and relationship goals. Over 16 months, 778 couples used the tool to create personalized prevention plans and agreements. The study mea…

This study tested a training program for family medicine doctors in Alabama to help them talk about HIV and STI prevention with teenage girls and young women. 46 doctors took part and completed surveys before and after training to see if their knowledge and practices changed. The…

This study tested how different doses of the antibiotic doxycycline reach tissues in the body. The goal is to combine it with HIV drugs into a single pill that could be taken just before sex to protect against both HIV and other sexually transmitted infections. 45 healthy adults …

This completed study in France looked at 248 people taking PrEP (a daily pill to prevent HIV) to see how their sexual behaviors and rates of other sexually transmitted infections (STIs) changed over time. Researchers compared those on PrEP for over a year to those on it for less …