SCHIZOPHRENIA AND RELATED DISORDERS
Clinical trials for SCHIZOPHRENIA AND RELATED DISORDERS explained in plain language.
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Could skipping a day of antipsychotics reduce side effects without worsening symptoms?
Disease control Recruiting nowThis study looks at whether taking antipsychotic medication every other day is as effective as taking it daily for people with schizophrenia. 120 participants will be randomly assigned to either daily dosing or every-other-day dosing for one year. The goal is to see if extended d…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Could early use of stronger drugs transform mental health treatment?
Disease control Recruiting nowThis study tests whether giving stronger medications earlier can help people with schizophrenia, major depression, or bipolar depression who did not get better with their first treatment. Over 1,200 participants will receive either standard second-line treatment or an intensified…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE3 • Sponsor: Dr. Inge Winter • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Could an antioxidant supplement boost brain function in schizophrenia?
Disease control Recruiting nowThis study tests whether MitoQ, an antioxidant supplement, can improve thinking and memory in people with early schizophrenia who have signs of mitochondrial dysfunction. Researchers will give 50 participants either MitoQ or a placebo daily for 12 weeks, alongside their usual med…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE2, PHASE3 • Sponsor: Mclean Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Could a quick switch to stronger meds change schizophrenia care?
Disease control Recruiting nowThis study looks at whether giving a more powerful medication sooner can help people with schizophrenia who did not get better on their first treatment. About 418 adults will either receive the usual second-line treatment or an early intensified approach. The goal is to see if th…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE4 • Sponsor: Dr. Inge Winter • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Molding minds: clay therapy tested for schizophrenia recovery
Symptom relief Recruiting nowThis study tests whether clay therapy can improve daily function and social performance in people with schizophrenia who are already on medication. Seventeen participants will take part in clay sessions, and researchers will measure changes in their ability to handle daily tasks …
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could magnetic pulses lift depression in schizophrenia?
Symptom relief Recruiting nowThis study tests whether repetitive transcranial magnetic stimulation (rTMS) can reduce depression in people with schizophrenia. About 180 adults will receive rTMS to the left prefrontal cortex. Researchers will measure changes in mood, thinking, and other symptoms over time.
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Can short bursts of exercise beat standard workouts for mental health?
Symptom relief Recruiting nowThis study tests whether brief high-intensity exercise is better than standard high-intensity training for people with schizophrenia or bipolar disorder. Fifty participants will follow one of the two programs for 26 weeks. The main goal is to see which program people stick with l…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: Haukeland University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Brain zaps for depression in schizophrenia: new trial underway
Symptom relief Recruiting nowThis study tests whether a brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help ease depression in people with schizophrenia. Researchers will give up to 20 sessions of active or sham rTMS to 120 participants and use brain scans to see h…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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30-Minute app aims to help At-Risk students sleep better and fight stigma
Symptom relief Recruiting nowThis study tests a 30-minute smartphone app designed to improve sleep and reduce stigma in college students who may be at risk for psychosis. About 115 students with poor sleep and certain experiences (like hearing voices or feeling paranoid) will use the app or wait to receive i…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Your words could reveal your risk: AI analyzes speech to predict psychosis
Knowledge-focused Recruiting nowThis study is testing whether subtle changes in how people speak can predict who will develop schizophrenia. Researchers will record and analyze free speech from 215 young people aged 15-30 who are at ultra-high risk for psychosis. By using computer programs to detect semantic an…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Loneliness may speed aging in schizophrenia, study suggests
Knowledge-focused Recruiting nowThis study looks at whether social isolation contributes to the early health problems seen in people with schizophrenia, who often die 10–20 years earlier than others. Researchers will follow 650 participants (500 with schizophrenia and 150 siblings) aged 40–70, tracking medical …
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC