Can targeted brain zaps quiet the voices in schizophrenia?

NCT ID NCT02916810

Recruiting now Symptom relief Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce auditory hallucinations in people with schizophrenia. The stimulation is personalized to each person's brain connectivity, targeting areas linked to their symptoms. Participants receive either active or sham rTMS over several weeks, and researchers measure changes in brain activity and symptom severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Repetitive transcranial magnetic stimulation (rTMS) — a non-invasive brain stimulation technique
What this could lead to: If successful, this could offer a new, personalized way to ease auditory hallucinations and improve attention and memory in people with schizophrenia.
What could go wrong: This is an early-stage trial, and results may not hold up in larger studies. rTMS is generally safe but can cause scalp discomfort or headaches.

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Conditions

The condition(s) this trial relates to.

Schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA AND RELATED DISORDERS

Contacts and locations

Locations

The University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States

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