Brain zaps for depression in schizophrenia: new trial underway

NCT ID NCT07060066

Recruiting now Symptom relief Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study tests whether a brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help ease depression in people with schizophrenia. Researchers will give up to 20 sessions of active or sham rTMS to 120 participants and use brain scans to see how it affects brain connections. The goal is to find a safe, effective way to treat depressive symptoms in this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS) using an H-coil device
What this could lead to: If successful, this could provide a new, non-drug treatment option for depression in people with schizophrenia.
What could go wrong: This is an early-stage study with no phase designation, so results are uncertain. The treatment is experimental and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA AND RELATED DISORDERS

Contacts and locations

Locations

The University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States

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