Could an antioxidant supplement boost brain function in schizophrenia?

NCT ID NCT06191965

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether MitoQ, an antioxidant supplement, can improve thinking and memory in people with early schizophrenia who have signs of mitochondrial dysfunction. Researchers will give 50 participants either MitoQ or a placebo daily for 12 weeks, alongside their usual medications. The goal is to see if MitoQ helps with cognitive skills like attention and problem-solving.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MitoQ (an antioxidant supplement)

What this could lead to

If it works, this could point toward a new way to improve thinking and memory in people with early schizophrenia.

What could go wrong

This is an early-phase trial with only 50 high-risk participants. MitoQ is a supplement, not a proven treatment, and may not improve cognition or symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • McLean Hospital

    RECRUITING

    Belmont, Massachusetts, 02478, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Lausanne

    NOT_YET_RECRUITING

    Lausanne, Switzerland

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Yale School of Medicine

    NOT_YET_RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••