Could a quick switch to stronger meds change schizophrenia care?

NCT ID NCT05958875

Recruiting now Disease control Sponsor: Dr. Inge Winter Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving a more powerful medication sooner can help people with schizophrenia who did not get better on their first treatment. About 418 adults will either receive the usual second-line treatment or an early intensified approach. The goal is to see if this strategy reduces symptoms and prevents hospital stays.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders schizoaffective disorder schizophrenia schizophreniform disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EARLY TREATMENT-RESISTANCE SCHIZOPHRENIA AND RELATED DISORDERS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Azienda Ospedaliero-Universitaria "Città della Salute e della Scienza di Torino"
RECRUITING

Turin, Italy

Contact Email: •••••@•••••
Bezirkskliniken Schwaben, Bezirkskrankenhaus Augsburg
NOT_YET_RECRUITING

Augsburg, 86156, Germany

Contact Email: •••••@•••••
Fundació Clínic per a la Recerca Biomèdica
RECRUITING

Barcelona, Spain

Contact Email: •••••@•••••
King's College London, Psychiatry & Cognitive Neuroscience
RECRUITING

London, SE5 8AF, United Kingdom

Contact Email: •••••@•••••

Contact Email: •••••@•••••
Klinik für Psychiatrie und Psychotherapie der Universitätsmedizin Mainz
RECRUITING

Mainz, Germany

Contact Email: •••••@•••••
LWL-Klinik Dortmund, Bereich Forschung & Wissenschaft
RECRUITING

Dortmund, 44287, Germany

Contact Email: •••••@•••••
Medical University Innsbruck
RECRUITING

Innsbruck, Austria

Contact Email: •••••@•••••
Universita degli Studi di Brescia
RECRUITING

Brescia, Italy

Contact Email: •••••@•••••
University Hospital Frankfurt am Main - Goethe University
RECRUITING

Frankfurt am Main, Germany

Contact Email: •••••@•••••
University of Cagliari
RECRUITING

Cagliari, Italy

Contact Email: •••••@•••••
Università degli studi della Campania Luigi Vanvitelli
RECRUITING

Naples, 80138, Italy

Contact Email: •••••@•••••
Universitätsklinik für Psychiatrie und Psychotherapie Bielefeld
RECRUITING

Bielefeld, Germany

Contact Email: •••••@•••••
Westfälische Wilhelms-Universität Münster
RECRUITING

Münster, Germany

Contact Email: •••••@•••••

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