RECURRENT GLIOBLASTOMA
Clinical trials for RECURRENT GLIOBLASTOMA explained in plain language.
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Sound waves open brain's shield to attack deadly tumors
Disease control CompletedThis early-phase study tested whether a focused ultrasound device can safely open the blood-brain barrier in 13 patients with recurrent glioblastoma, a severe brain cancer. The goal was to let the chemotherapy drug carboplatin reach the tumor more effectively. The study focused o…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated May 17, 2026 00:28 UTC
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Sound waves and radiation team up against returning brain tumors
Disease control CompletedThis small pilot study tested whether combining focused ultrasound with a second round of radiation is safe for people with recurrent glioblastoma, an aggressive brain cancer. Seven adults who had already tried standard treatments received the combination therapy. The goal was to…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: NA • Sponsor: NaviFUS Corporation • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Sound waves open brain barrier to attack deadly tumors
Disease control CompletedThis study tested whether a special ultrasound device can safely and temporarily open the blood-brain barrier in people with recurrent glioblastoma, a type of brain cancer. The goal was to let the chemotherapy drug carboplatin reach the tumor more effectively. 28 participants wer…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Experimental combo targets Hard-to-Treat brain tumors
Disease control CompletedThis early-phase study tested two drugs, ASP8374 and cemiplimab, in 14 people with recurrent glioblastoma, an aggressive brain cancer. The goal was to find a safe dose and see if giving the drugs before surgery could increase cancer-fighting immune cells in the tumor. While not a…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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New imaging agent could sharpen detection of recurrent brain cancer
Diagnosis CompletedThis study tested a special dye called fluoroethyltyrosine (FET) used during a PET scan to see if it can better detect brain tumors that have come back after treatment. Researchers enrolled 143 people with suspected recurrent brain tumors. The goal was to see how accurate the FET…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated May 13, 2026 15:58 UTC
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Brain cancer pilot explores tailored drug cocktails
Knowledge-focused CompletedThis study tested whether it's possible to create and start personalized treatment plans quickly for adults with recurrent glioblastoma, a serious brain cancer. Researchers used a special genetic test on tumor tissue to find specific DNA changes and match patients to targeted dru…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Jennifer Clarke • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC