RECTAL NEOPLASMS

This study is testing whether a specific type of internal radiation boost (called CXB) given after standard chemo-radiation is better than an external radiation boost at helping patients with early rectal cancer avoid major surgery that removes the rectum or requires a permanent …

This study is testing whether adding a new immunotherapy drug (tiragolumab) to an existing one (atezolizumab) can help eliminate rectal cancer more effectively after patients receive standard chemoradiation. The goal is to see if the drugs can destroy all cancer cells in the remo…

This study is testing whether a modified surgical stitching method is safer than the current standard technique for patients having minimally invasive rectal cancer surgery. Researchers want to see if the new method reduces the risk of dangerous leaks where the bowel is reconnect…

This study is comparing two ways of reconnecting the bowel during surgery for low rectal cancer. One method is the standard approach, and the other adds 8-10 extra stitches to reinforce the connection. The goal is to see if the reinforced method is better at preventing a serious …

This study is testing whether adding chlorophyllin, a compound from green leaves, to standard rectal cancer treatment can reduce severe side effects like nausea, diarrhea, and blood problems. About 76 patients with locally advanced rectal cancer will receive either chlorophyllin …