RECTAL NEOPLASMS
Clinical trials for RECTAL NEOPLASMS explained in plain language.
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Immunotherapy combo aims to wipe out rectal cancer after radiation
Disease control OngoingThis study tests whether adding two immunotherapy drugs (atezolizumab and tiragolumab) after standard chemoradiation can help eliminate rectal cancer in people with locally advanced disease. About 58 adults with resectable rectal cancer will receive either the drug combination or…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 17, 2026 00:31 UTC
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New combo therapy aims to save rectums from radical surgery
Disease control OngoingThis study tests whether a short course of radiation or standard chemoradiation, followed by a strong chemotherapy cocktail (mFOLFOXIRI), can help people with low rectal cancer avoid major surgery. The goal is to preserve the rectum and its function. About 66 adults with stage 2-…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Pei-Rong Ding • Aim: Disease control
Last updated May 17, 2026 00:30 UTC
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New radiation technique may help rectal cancer patients avoid surgery
Disease control OngoingThis study tests whether a special type of internal radiation (contact X-ray brachytherapy) can help more people with early rectal cancer keep their rectum compared to standard external radiation. About 148 adults with small, early-stage tumors will receive standard chemoradiatio…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE3 • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated May 17, 2026 00:30 UTC
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New staple technique aims to cut dangerous leaks in rectal cancer surgery
Disease control ENROLLING_BY_INVITATIONThis study compares a new stapling method (MST) to the standard method (DST) for reconnecting the bowel after rectal cancer surgery. The goal is to see if MST lowers the chance of a leak at the connection site, which can cause serious problems. About 450 adults having minimally i…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Korea University Anam Hospital • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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Robot-Assisted surgery aims to improve rectal tumor removal
Disease control OngoingThis study tests a new robotic surgery method for removing rectal tumors. The goal is to make the surgery safer and more precise by using a single-port robot that gives better vision and flexibility. Twenty participants with benign or early-stage rectal tumors will be treated, an…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Jeng-Fu You • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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Extra stitches may cut dangerous leaks after rectal cancer surgery
Disease control ENROLLING_BY_INVITATIONThis study tests whether adding extra stitches around the surgical connection (anastomosis) during laparoscopic low rectal cancer surgery can reduce the risk of leakage, a serious complication. About 300 adults with low rectal cancer will be assigned to either the standard proced…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Shanghai 10th People's Hospital • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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Could a plant compound ease harsh cancer therapy side effects?
Symptom relief OngoingThis study tests whether adding chlorophyllin, a natural compound, to standard cancer treatment can lower side effects like bowel, bladder, and blood problems in people with advanced rectal cancer. About 76 adults will receive either chlorophyllin or a placebo alongside their usu…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Tata Memorial Centre • Aim: Symptom relief
Last updated May 17, 2026 00:40 UTC