RADIATION THERAPY

This trial is testing whether adding the chemotherapy drug docetaxel after standard treatment (radiation or surgery) can improve outcomes for men with a particularly aggressive form of prostate cancer (Gleason score 9-10). Participants will either receive standard treatment alone…

This study tests whether combining a special PET scan (CAIX PET/CT) with standard therapy can better control advanced kidney cancer. About 70 adults with recurrent or metastatic clear cell renal cell carcinoma will receive targeted therapy and immunotherapy, plus precise radiatio…

This study tests whether adding precise, high-dose radiation (SBRT) to standard hormone therapy can delay cancer progression in men with prostate cancer that has spread to 1-3 spots. About 118 participants will be randomly assigned to get SBRT plus standard care or standard care …

This study looks at whether adding a precise type of radiation (SABR) to standard drug therapy (targeted therapy plus immunotherapy) can help people with recurrent or metastatic kidney cancer live longer without their disease getting worse. About 300 participants will be enrolled…

This phase II trial tests whether adding a special low-dose radiation therapy to standard chemotherapy and an immunotherapy drug can improve treatment for a type of colon cancer that usually doesn't respond well to immunotherapy alone. The study enrolls 38 adults with high-risk, …

This trial is testing whether advanced PET-CT scans can spot early signs of heart damage caused by standard radiation therapy for locally advanced non-small cell lung cancer. Ten adults with stage III lung cancer will receive a special PET-CT scan before and three months after th…

This study tests a new type of PET/MRI scan to see if it can better tell the difference between a growing brain tumor and changes caused by radiation or immunotherapy. About 30 adults with brain metastases who have had radiation in the last 2 years will get a single 3-hour scan s…

This study compares two standard radiation methods—proton therapy and photon therapy—for women with newly diagnosed cervical or endometrial cancer. The goal is to see which approach causes fewer stomach and bowel side effects. About 116 participants will be randomly assigned to o…

This study tests whether a personalized activity coaching program can help women feel less tired during pelvic radiation therapy for endometrial cancer. Sixteen participants will be randomly assigned to receive coaching or usual care. The main goal is to see if the program is pra…

This study tests whether wearing a virtual reality (VR) headset during daily radiation therapy can help manage anxiety in people with prostate, breast, lung, or head and neck cancer. About 54 patients will use a Meta Quest 2 headset during their treatments, and researchers will t…

This study tests a cooling device placed inside the mouth during radiation therapy for larynx cancer. The goal is to see if cooling can protect taste buds from radiation damage and prevent loss of taste. About 15 adults with advanced larynx cancer will try the device and report t…

This study at Memorial Sloan Kettering Cancer Center is testing new ways to use MRI and CT scans to improve radiation therapy planning and tumor response checks. About 837 adults, including healthy volunteers and cancer patients, will undergo extra scans over time. The goal is to…

This study tests whether cancer patients undergoing radiation therapy can use a mobile app called myCircadian Clock to record everything they eat and drink (except water and medications). Twenty adults starting radiation for cancer will use the app throughout their treatment. The…

This study compares two ways of outlining tumors for breast cancer radiation: one done entirely by hand by a doctor, and one where artificial intelligence (AI) helps create the outline. The goal is to see if AI-assisted contouring is just as good and whether it saves time. About …