PURE AUTONOMIC FAILURE
Clinical trials for PURE AUTONOMIC FAILURE explained in plain language.
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Could a sleep apnea machine fix nighttime blood pressure and morning dizziness?
Symptom relief Recruiting nowThis study looks at whether using a CPAP machine (commonly used for sleep apnea) can lower high blood pressure when lying down at night and help with dizziness upon standing in people with autonomic failure. About 59 adults aged 40-80 with conditions like Parkinson's disease or m…
Matched conditions: PURE AUTONOMIC FAILURE
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Heat therapy may tame dangerous nighttime blood pressure spikes
Symptom relief Recruiting nowThis study tests whether applying gentle heat to the belly overnight can safely lower high blood pressure in people with autonomic failure who also have high blood pressure when lying down. About 20 adults with conditions like Parkinson's or Multiple System Atrophy will be monito…
Matched conditions: PURE AUTONOMIC FAILURE
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 11, 2026 20:48 UTC
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Rare disease study probes inner workings of blood pressure drugs
Knowledge-focused Recruiting nowThis study looks at how two medications, midodrine and droxidopa, affect the veins in the abdomen of people with autonomic failure—a condition where the body can't control blood pressure properly. Researchers will measure changes in heart function when participants are tilted upr…
Matched conditions: PURE AUTONOMIC FAILURE
Phase: PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 13:01 UTC
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Brain scan study aims to predict Parkinson's risk in autonomic failure patients
Knowledge-focused Recruiting nowThis study uses a special PET scan to measure dopamine production in the brains of people with autonomic failure, including those with Parkinson's disease, Multiple System Atrophy, or Dementia with Lewy Bodies. The goal is to find early signs that predict if a person with pure au…
Matched conditions: PURE AUTONOMIC FAILURE
Phase: PHASE1 • Sponsor: Daniel Claassen • Aim: Knowledge-focused
Last updated May 17, 2026 12:53 UTC