PULMONARY FIBROSIS

This study tested a single infusion of stem cells from donated umbilical cord tissue in people with severe scleroderma that also affects the lungs. The goal was to see if the treatment could improve lung function, exercise ability, and quality of life. Only one person took part, …

This study tested whether nintedanib, a drug used for lung scarring, could slow lung damage in people who had severe COVID-19 and still had lung problems more than 30 days later. 103 adults who needed oxygen or had low oxygen levels joined the trial. The main goal was to see if t…

This small pilot study looked at whether the drug pirfenidone is safe and effective for people with a specific type of lung scarring (pulmonary fibrosis) linked to certain antibodies (anti-MPO) or a related blood vessel condition. Seven adults took part, and the main goal was to …

This study tested an experimental drug called BMS-986278 in 403 adults with pulmonary fibrosis, a condition that causes lung scarring and breathing problems. The goal was to see if the drug could improve lung function and check for side effects. Participants took the drug or a pl…

This early-stage study tested the safety and how the body handles an experimental inhaled drug called CHF10073. It involved 155 healthy volunteers who received single or multiple doses. The goal was to check for side effects and measure drug levels, not to treat the disease. This…

This study looked at the genetics of a rare lung condition called combined pulmonary fibrosis and emphysema (CPFE), which causes severe breathing problems mostly in smokers. Researchers compared 250 people with CPFE, other lung diseases, or healthy lungs to see if those with CPFE…

This study followed 51 people with idiopathic pulmonary fibrosis (IPF) for 6 months to understand how their shortness of breath changes over time. Researchers measured both the physical sensation and emotional impact of breathlessness using questionnaires. The goal was to link th…

This early-stage study tested a new drug called 9MW3811 in 32 healthy adults to see if it is safe and how the body handles it. The drug is being developed for lung scarring (pulmonary fibrosis) and tumors. This first step in humans focused only on safety and drug levels, not on t…

This study followed 38 adults who survived severe H1N1 flu that caused lung failure. Researchers compared those who needed a machine to add oxygen to their blood with those who did not. They measured lung function, quality of life, and mental health at least 9 months after leavin…