PULMONARY FIBROSIS

This small study tested whether a drug called pirfenidone could safely slow the progression of lung scarring (pulmonary fibrosis) in patients who also have a specific immune system marker or related blood vessel inflammation. The trial involved 7 adults with this specific conditi…

This study tested whether an experimental drug called BMS-986278 could help people with pulmonary fibrosis, a condition that causes scarring in the lungs. 403 participants were randomly assigned to receive either the drug or a placebo for 26 weeks to see if it could slow the decl…

This was the first time a new drug called 9MW3811 was given to people. The main goal was to check if it was safe and how the body handled it in 32 healthy adult volunteers. This early safety study is a necessary first step before testing if the drug can help treat conditions like…

This study followed people who survived a life-threatening lung injury from the 2009 H1N1 flu. Researchers compared two groups: those who needed a special life-support machine and those who did not. They checked lung function, quality of life, and mental health to understand the …

This study aimed to understand the genetic factors behind Combined Pulmonary Fibrosis and Emphysema (CPFE), a severe lung disease mostly affecting smokers. Researchers compared 250 people, including patients with CPFE, other lung conditions, and healthy individuals, to see if tho…

This early-stage study tested the safety and how the body processes an inhaled drug called CHF10073, which is being developed for pulmonary fibrosis (lung scarring). It involved 155 healthy volunteers to check for side effects and measure drug levels in the blood and lungs. The m…