Umbilical cord stem cells tested for rare lung condition

NCT ID NCT07542067

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a single intravenous infusion of stem cells from donated umbilical cord tissue in one person with severe scleroderma that had caused lung scarring and high blood pressure in the lungs. The goal was to see if the treatment could improve lung function, exercise ability, and quality of life. Because only one person took part and there was no comparison group, the results are very preliminary and cannot be generalized.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mesenchymal stem cells from donated umbilical cord tissue (Wharton's jelly)
What this could lead to
If this approach works, it could point toward a new treatment option for people with severe scleroderma that affects the lungs and has not responded to standard therapies.
What could go wrong
This was a very early, tiny study (only 1 participant) with no control group. The results may not apply to other patients, and the treatment may not work or could cause side effects like fever.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinica Universidad de La Sabana

    Bogotá, Bogota D.C., 110131, Colombia

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