PSYCHOSIS

This study tests whether intensive family therapy can help young people at high risk for developing psychosis. 220 youth ages 13-25 will receive either 18 family therapy sessions or 3 family sessions plus individual support over 6 months, with follow-up for 18 months. The goal is…

This study is testing whether a 12-week mobile app program can help improve thinking skills and motivation in young adults recently diagnosed with psychosis. The program is given alongside standard care, which includes therapy and medication management. Researchers will compare t…

This study is checking if a 16-week program of combined high-intensity cardio and strength training is a practical and acceptable option for adults with psychotic disorders. It involves 40 participants who are patients at a specific mental health center. The main goal is to see i…

This study is testing a therapy called imagery rescripting to see if it can help people with early psychosis. Eight participants will receive the therapy, which involves working with a practitioner to change distressing mental images. The main goal is to see if this improves thei…

This study is testing whether a specific talk therapy for insomnia (CBT-I) can help Veterans who have both psychosis and trouble sleeping. The goal is to see if improving their sleep also helps their overall mental and physical health and daily functioning. Researchers are compar…

This study is testing a support program for teens and young adults (ages 12-25) who are at high risk for developing psychosis and have had recent suicidal thoughts. The program involves training nominated family members or friends to provide better support, aiming to reduce feeli…

This study is testing whether a creative writing group program helps people with serious mental illnesses like schizophrenia, bipolar disorder, or severe depression. About 300 participants will either join the writing groups along with their usual care or continue with usual care…

This study uses repeated brain scans to understand why standard antipsychotic medications don't work well for many people experiencing their first episode of psychosis. Researchers will follow 156 young adults who have never taken these medications, scanning their brains four tim…

This study aims to understand how memory works in the brains of people with early psychosis. Researchers will use a non-invasive magnetic stimulation device (TMS) and MRI brain scans on 20 participants. The goal is to gather knowledge about brain connections, not to provide treat…

This large international study aims to understand and predict the future for young people at clinical high risk for psychosis. Researchers are collecting detailed information from nearly 2,000 at-risk participants and 640 healthy volunteers over two years to develop prediction to…

This study aimed to understand if body temperature patterns differ in young adults experiencing their first episode of psychosis compared to those without psychosis. Researchers planned to measure temperature continuously for 24-36 hours using a special sensor and track symptoms …