PERIAPICAL PERIODONTITIS
Clinical trials for PERIAPICAL PERIODONTITIS explained in plain language.
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New antibiotic paste could replace drilling for Kids' cavities
Disease control CompletedThis study tested a new, less invasive way to treat infected baby molars in children aged 4 to 10. Instead of fully cleaning out the tooth canals (standard pulpectomy), the new method uses an antibiotic paste to kill infection without drilling. The study involved 110 children and…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: taymour abuawwad • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Root canal showdown: one visit or two? new study has answers
Disease control CompletedThis study looked at whether a root canal for an infected tooth with an abscess can be done in one visit instead of two. Fifty-nine adults received either a single-visit treatment or a two-visit treatment with a calcium hydroxide medication placed in between. After 12 months, bot…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New dental technique helps regrow roots in young teeth
Disease control CompletedThis study tested three different materials (blood clot, platelet-rich fibrin, and concentrated growth factor) combined with two types of rinses to help regrow root tissue in 30 immature permanent teeth with dead nerves. Participants aged 9 to 25 were followed for 12 months using…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Kahramanmaras Sutcu Imam University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can a laser beam replace painkillers after dental surgery?
Symptom relief CompletedThis trial asks whether photobiomodulation — a type of low-level laser therapy — can lessen pain and swelling after endodontic (root-end) surgery. Thirty-four adults needing surgery on an upper tooth will be randomly assigned to receive either the laser treatment or a sham proced…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: University of Nove de Julho • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Precision dental surgery boosts healing and comfort
Symptom relief CompletedThis study tested a more precise dental surgery for people with persistent root infections after standard treatment. Using a 3D-printed guide, surgeons aimed to remove infected tissue more accurately, reduce surgery time, and improve quality of life. The trial involved 70 adults …
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
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Chill out tooth pain: cooling inside of tooth during root canal may ease ache
Symptom relief CompletedThis study tests whether using cooled liquid to clean the inside of a tooth during root canal treatment can reduce pain afterward. It includes adults with certain tooth conditions who need a root canal. The approach involves comparing cooled versus room-temperature irrigation to …
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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Could a simple injection make root canals less painful?
Symptom relief CompletedThis trial tests whether a corticosteroid injection given before root canal treatment can reduce pain and inflammation afterward. One hundred adults with symptomatic pulpitis (tooth nerve inflammation) are randomly assigned to receive either standard root canal treatment alone or…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Istanbul Medipol University Hospital • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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New tooth-cleaning methods could speed healing of serious infections
Symptom relief CompletedThis study looked at five different methods for cleaning infected root canals in 132 people with large tooth infections. The goal was to see which technique helps the infection heal best by reducing the size of the infection site on X-rays. The methods included manual cleaning, u…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Tooth infection study reveals key inflammation clues
Knowledge-focused CompletedThis study looked at 185 people to compare inflammation markers in those with tooth infections (apical periodontitis), gum disease (chronic periodontitis), and healthy gums. Researchers measured substances like TNF-α and PGE2 in blood and gum fluid. The goal was to better underst…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Istanbul Medipol University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC