OVERWEIGHT , OBESITY

This Phase 2 study tests whether ZT006, a daily or weekly tablet, helps overweight and obese adults lose weight when combined with diet and exercise. About 184 participants will receive either ZT006 or a placebo for 28 weeks, with some continuing for an extra 12 weeks. The main g…

This study tests whether a probiotic supplement containing Bifidobacterium longum can help overweight or obese children aged 3 to 14 improve their body mass index (BMI). Sixty children will receive either the probiotic or a placebo for 8 weeks, along with lifestyle advice. Resear…

This study is testing a new probiotic called CLB101TM in healthy but overweight adults who have digestive issues like bloating or stomach pain. The probiotic is designed to produce a natural substance called butyrate, which may help strengthen the gut lining and support immune he…

This study tests a smartphone app called eTRIP, which uses artificial intelligence to help people with overweight or obesity make healthier food choices and stick to their weight loss goals. Some participants also wear a continuous glucose monitor for 10 days to see how their blo…

This study looks at how eating mostly ultra-processed foods (like packaged snacks) compared to less-processed foods (like whole fruits and vegetables) affects blood pressure and other heart health markers. About 79 overweight adults will follow special diets to see the difference…

This study looks at whether reducing exposure to everyday chemicals called endocrine disruptors (found in plastics, cosmetics, and food) can help people with overweight or obesity lose weight. About 226 participants will either follow a program to lower chemical exposure or use a…

This study planned to analyze data from a large U.S. health survey to see if eating a diet rich in antioxidants is linked to better metabolic health in overweight or obese adults. Researchers would have looked at body mass index and markers like blood sugar and cholesterol. Howev…

This study looks at why people who lose weight often experience a greater-than-expected slowdown in metabolism, making it harder to keep weight off. Researchers will compare three lifestyle approaches—resistance training, calorie restriction, and time-restricted eating—in 75 over…