New Weight-Loss drug zovaglutide enters final testing phase

NCT ID NCT07230119

First seen Jun 26, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This Phase 3 trial tests whether zovaglutide, given as a shot every 4 weeks, helps people with overweight or obesity lose weight. About 744 adults will receive either the drug or a placebo for 52 weeks. The study measures how much weight they lose and how many achieve at least 5% weight loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
zovaglutide
What this could lead to
If successful, zovaglutide could offer a new, effective weight-loss option for people with overweight or obesity, helping them lose significant weight.
What could go wrong
This is a Phase 3 trial, but results are not yet known. The drug may not work better than placebo, and side effects are possible. Long-term safety and effectiveness are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijiing, 100050, China

  • Binzhou Medical University Hospital

    Binzhou, Shandong, 256603, China

  • Central Hospital Affiliated to Shandong First Medical University

    Jinan, Shandong, 250000, China

  • First Hospital of Qinhuangdao

    Qinhuangdao, Hebei, 066000, China

  • Gansu Provincial Hospital

    Lanzhou, Gansu, 730099, China

  • Guangzhou Red Cross Hospital

    Guangzhou, Guangdong, 510235, China

  • Handan First Hospital

    Handan, Hebei, 056002, China

  • Harbin Medical University Affiliated Fourth Hospital

    Harbin, Heilongjiang, 150001, China

  • Hebei Petro China Cental Hospital

    Langfang, Hebei, 065000, China

  • Huizhou Central People's Hospital

    Huizhou, Guangdong, 516008, China

  • Huzhou Central Hospital

    Huzhou, Zhejiang, 313000, China

  • Jiangxi Provincial People's Hospital

    Nanchang, Jiangxi, 330006, China

  • Jilin Province FAW General Hospital

    Changchun, Jilin, 130011, China

  • Jincheng General Hospital

    Jincheng, Shanxi, 48006, China

  • Luoyang Third People's Hospital

    Luoyang, Henan, 471002, China

  • Nanjing Jiangning Hospital

    Nanjing, Jiangsu, 210000, China

  • Nanyang Second People's Hospital

    Nanyang, Henan, 473009, China

  • Peking University People's Hospital

    Beijing, China

  • Sanmenxia Central Hospital

    Sanmenxia, Henan, 472000, China

  • The 2nd People's Hospital of Chengdu

    Chengdu, Sichuan, 610021, China

  • The Affiliated Hospital of Xuzhou Medical University

    Xuzhou, Jiangsu, 221006, China

  • The Fifth People's Hospital of Shenyang

    Shenyang, Liaoning, 110023, China

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

  • The First Affiliated Hospital of Henan University of Science & Technology

    Luoyang, Henan, 471000, China

  • The First Affiliated Hospital of Ningbo University

    Ningbo, Zhejiang, 315010, China

  • The First Affiliated of Nanyang Medical College

    Nanyang, Henan, 473000, China

  • The First People's Hospital of Changde

    Changde, Hunan, 415003, China

  • The Second Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, 210011, China

  • The Second Affiliated Hospotal of Guangxi Medical University

    Nanning, Guangxi, 530006, China

  • The Second Hospital of Hebei Medical University

    Shijiangzhuang, Hebei, 050005, China

  • The Second People's Hospital of Lianyungang

    Lianyungang, Jiangsu, 222002, China

  • The Second People's Hospital of Yibin

    Yibin, Sichuan, 644000, China

  • The Third Affiliated Hospital of Jinzhou Medical University

    Jinzhou, Liaoning, 121002, China

  • Wuhan No.3 Hospital

    Wuhan, Hubei, 430060, China

  • Xi'an Daxing Hospital

    Xi’an, Shanxi, 710000, China

  • Xuancheng People's Hospital

    Xuancheng, Anhui, 242099, China

  • Yan'an University Xianyang Hospital

    Yanan, Shanxi, 712000, China

  • Yichang Central People's Hospital

    Yichang, Hubei, 443003, China

  • Yichang Central People's Hospital (Xiling Campus)

    Yichang, Hubei, 443000, China

  • Yueyang Central Hospital

    Yueyang, Hunan, 414000, China

  • Yueyang People's Hospital

    Yueyang, Hunan, 414022, China

  • Yuncheng Central Hospital

    Yuncheng, Shanxi, 44099, China

  • Zhuzhou Central Hospital

    Zhuzhou, Hunan, 412007, China

  • Zibo Central Hospital

    Zibo, Shandong, 255036, China

  • Zibo Municipal Hospital

    Zibo, Shandong, 255400, China

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