OPIOID USE DISORDER (OUD)
Clinical trials for OPIOID USE DISORDER (OUD) explained in plain language.
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Nurses take the lead in methadone care to keep patients in treatment
Disease control Recruiting nowThis study tests whether nurses in addiction centers can manage the start of methadone treatment for people with opioid use disorder. The goal is to see if this approach helps more patients stay in care for at least 3 months. The study will involve 182 adults starting methadone f…
Matched conditions: OPIOID USE DISORDER (OUD)
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Brain zaps to beat opioid cravings: experimental therapy recruits 6 patients
Disease control Recruiting nowThis study tests whether personalized deep brain stimulation (DBS) is safe and can reduce cravings and opioid use in people with severe, treatment-resistant opioid use disorder. Six adults aged 22–75 who have used opioids for over 5 years will undergo brain mapping to identify cr…
Matched conditions: OPIOID USE DISORDER (OUD)
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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CBD shows promise in opioid relapse prevention trial
Disease control Recruiting nowThis study tests whether cannabidiol (CBD) can reduce cravings and prevent relapse in people with opioid use disorder who are already on medication like methadone or buprenorphine. About 450 adults will take CBD or a placebo for 24 weeks while continuing their usual treatment. Th…
Matched conditions: OPIOID USE DISORDER (OUD)
Phase: PHASE3 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated May 05, 2026 11:54 UTC
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New study aims to speed up methadone start for fentanyl users
Disease control Recruiting nowThis study looks for a safe and effective way to start methadone treatment faster for people with opioid use disorder who also use fentanyl. Researchers will test different starting doses in 24 adults to see which one works best without causing serious side effects. The goal is t…
Matched conditions: OPIOID USE DISORDER (OUD)
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Texting your way to recovery: mindfulness messages may boost opioid treatment
Symptom relief Recruiting nowThis study tests whether daily text reminders and mindfulness messages can help 60 adults taking medication for opioid use disorder stick to their treatment and better manage cravings, pain, and withdrawal symptoms. Participants receive medication reminders for 6 months and up to…
Matched conditions: OPIOID USE DISORDER (OUD)
Phase: NA • Sponsor: University of New Mexico • Aim: Symptom relief
Last updated May 17, 2026 10:39 UTC
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Brain scans reveal Ibogaine's effects on opioid cravings
Knowledge-focused Recruiting nowThis study looks at how ibogaine, a plant-based compound, affects brain activity and reduces cravings in people with moderate to severe opioid use disorder. Twenty adults who are already scheduled to receive ibogaine treatment at a licensed clinic in Mexico will undergo brain sca…
Matched conditions: OPIOID USE DISORDER (OUD)
Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC