Brain pacemaker aims to curb opioid cravings in small trial

NCT ID NCT07214467

First seen Nov 01, 2025 · Last updated Jun 07, 2026 · Updated 34 times

Summary

This study tests whether personalized deep brain stimulation (DBS) can safely reduce cravings and opioid use in people with severe, treatment-resistant opioid use disorder. Six adults aged 22-75 who have used opioids for over 5 years and have not responded to other treatments will receive brain mapping and then adaptive DBS. The goal is to find brain signals linked to craving and use stimulation to control them, but this is an early safety and feasibility study, not a cure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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