Brain scans reveal Ibogaine's effects on opioid cravings
NCT ID NCT07226570
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study uses brain scans (MRI, MRS, EEG) to see how ibogaine affects the brain in 20 people with moderate to severe opioid use disorder. Participants will already be receiving legal ibogaine treatment outside the U.S. The research team only observes and measures brain activity, cravings, and withdrawal symptoms before and after treatment. The goal is to understand how ibogaine might work in the brain, not to test if it is a safe or effective treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ibogaine
What this could lead to
If successful, this study could help explain how ibogaine affects the brain in opioid use disorder, potentially guiding future treatments.
What could go wrong
This is a very small observational study (20 people) where researchers do not provide the treatment. It cannot prove ibogaine works or is safe, only explore brain changes.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OPIOID USE DISORDER (OUD) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Susan Samueli Integrative Health Institute, University of California, Irvine
RECRUITINGIrvine, California, 92617, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact