Nurses take the lead: could nurse-led methadone dosing keep more people in treatment?

NCT ID NCT07085377

Recruiting now Disease control Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This study tests a new approach where nurses, rather than doctors, adjust methadone doses for people starting treatment for opioid addiction. The goal is to see if this makes it easier for patients to stay in care for at least three months. The trial will enroll 182 adults in French addiction centers and compare the nurse-led method to usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: methadone
What this could lead to: If successful, this could make methadone treatment more accessible and flexible, helping more people stay in care for opioid addiction.
What could go wrong: This is a small, early-stage study in France, so results may not apply elsewhere. The approach relies on nurse training and local regulations, which may limit broader use.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADDICTOLOGY OPIOID USE DISORDER (OUD)

Contacts and locations

Locations

CSAPA de Brioude
NOT_YET_RECRUITING

Brioude, 43100, France
CSAPA du Griffon, Oppelia Aria 69
RECRUITING

Villeurbanne, 69100, France
CSAPA, Association Bizia, Centre Hospitalier de la Côte Basque
RECRUITING

Bayonne, 64109, France
CSAPA, Association Nationale de Prévention en Alcoologie et Addictologie (ANPAA), Résidence Le Victor Hugo
NOT_YET_RECRUITING

Le Puy-en-Velay, 43000, France
CSAPA, Hôpital de la Croix Rousse, Hospices Civils de Lyon
RECRUITING

Lyon, 69004, France
CSAPA, Service Universitaire d'Addictologie de Lyon, Hôpital Edouard Herriot, Hospices Civils de Lyon
RECRUITING

Lyon, 69003, France
CSAPA, Service d'Addictologie, Centre Hospitalier Charles Perrens, CHU de Bordeaux
NOT_YET_RECRUITING

Bordeaux, 33000, France
CSAPA, Service de Psychiatrie et d'Addictologie, Hôpital Civil, CHRU de Strasbourg
NOT_YET_RECRUITING

Strasbourg, 690910, France

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