A bold community experiment takes on the opioid crisis

NCT ID NCT04111939

Completed Prevention Sponsor: RTI International Source: ClinicalTrials.gov ↗

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial tests whether a comprehensive, community-wide strategy can reduce opioid overdose deaths by 40% in 67 communities hardest hit by the crisis. The approach, called Communities That HEAL, brings together local leaders, healthcare, justice, and community groups to implement a menu of evidence-based practices and a public communications campaign. The goal is to see if this integrated model can save lives on a large scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Communities That HEAL (CTH) intervention - a community-engaged program combining stakeholder engagement, evidence-based practices, and a communications campaign to address opioid addiction.
What this could lead to: If successful, this approach could provide a blueprint for communities nationwide to significantly cut opioid overdose deaths.
What could go wrong: This is a large, complex community-level trial, and results may vary across different settings. Success depends on many factors beyond the intervention itself, such as local resources and cooperation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPIOID USE DISORDER (OUD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Behavior, Addictive Drug Overdose opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID USE DISORDER (OUD)

Contacts and locations

Locations

Boston Medical Center

Boston, Massachusetts, 02118, United States
Columbia University

New York, New York, 10027, United States
Ohio State University

Columbus, Ohio, 43210, United States
University of Kentucky

Lexington, Kentucky, 40508, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.