OPEN-ANGLE GLAUCOMA
Clinical trials for OPEN-ANGLE GLAUCOMA explained in plain language.
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Eye implant could replace daily drops for glaucoma patients
Disease control CompletedThis early-stage study tested a tiny implant placed inside the eye that slowly releases medication to lower eye pressure in people with mild-to-moderate open-angle glaucoma. The goal was to find a safe and effective dose that reduces pressure by more than 20% with few side effect…
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: PHASE1 • Sponsor: PolyActiva Pty Ltd • Aim: Disease control
Last updated May 17, 2026 07:50 UTC
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New eye drops show promise for glaucoma patients
Disease control CompletedThis study tested two new eye drops (AR-17043 and a combination with latanoprost) to see if they safely lower eye pressure in people with open-angle glaucoma or high eye pressure. A total of 426 adults took part. The goal was to find the best dose for reducing pressure, which is …
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: PHASE2 • Sponsor: Alcon Research • Aim: Disease control
Last updated May 17, 2026 07:34 UTC
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Laser location may matter for glaucoma control
Disease control CompletedThis study tested whether aiming a laser (SLT) at the nasal or inferior part of the eye works better to lower pressure in open-angle glaucoma. 13 adults with high eye pressure received one of the two treatments. The main goal was to see which location reduces eye pressure more ef…
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: NA • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New gel stent offers hope for glaucoma patients
Disease control CompletedThis study tested a gel stent implant placed outside the eye to lower eye pressure in people with open-angle glaucoma. About 74 adults aged 45 and older took part. The goal was to see if the stent safely reduces eye pressure by at least 20% while using the same or fewer glaucoma …
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: PHASE3 • Sponsor: AbbVie • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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Mini stent offers new hope for glaucoma patients
Disease control CompletedThis study tested a small device called the Hydrus Microstent in 217 adults with open-angle glaucoma that was not well controlled with medication. The goal was to see if the implant could safely lower eye pressure and reduce the number of eye drops needed. Results showed that man…
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: NA • Sponsor: Ivantis, Inc. • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New eye drop shows promise for glaucoma patients
Disease control CompletedThis study tested a new eye drop called Reformulated PG324 to see how safe and effective it is at lowering eye pressure in people with open-angle glaucoma or ocular hypertension. About 489 participants took part. The goal is to help control the disease and prevent vision loss, bu…
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: PHASE3 • Sponsor: Alcon Research • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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New eye drop shows promise in lowering glaucoma pressure
Disease control CompletedThis study tested a new eye drop, NCX 470, against a standard treatment (latanoprost) in 696 people with open-angle glaucoma or high eye pressure. Participants used the drops once daily for up to 12 months. The main goal was to see how well NCX 470 lowers eye pressure compared to…
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: PHASE3 • Sponsor: Nicox Ophthalmics, Inc. • Aim: Disease control
Last updated May 06, 2026 16:15 UTC
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Eye drop study reveals how NCX 470 lowers pressure in glaucoma
Knowledge-focused CompletedThis study looked at how NCX 470 eye drops affect fluid movement inside the eye. 18 healthy volunteers or people with high eye pressure received the drops or a placebo for 8 days. Researchers measured fluid flow and drainage to understand how the drops work.
Matched conditions: OPEN-ANGLE GLAUCOMA
Phase: PHASE2, PHASE3 • Sponsor: Nicox Ophthalmics, Inc. • Aim: Knowledge-focused
Last updated May 11, 2026 20:37 UTC