New eye drop shows promise for glaucoma patients in large trial

NCT ID NCT07082816

Completed Disease control Sponsor: Alcon Research Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new eye drop called Reformulated PG324 to see how well it lowers eye pressure in people with open-angle glaucoma or high eye pressure. About 489 adults took part. The goal was to measure the drop's safety and effectiveness in controlling eye pressure, which is key to managing these conditions.

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Conditions

The condition(s) this trial relates to.

glaucoma ocular hypertension open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OCULAR HYPERTENSION OPEN-ANGLE GLAUCOMA

Contacts and locations

Locations

Albemarle Eye Center

Elizabeth City, North Carolina, 27909, United States
CORE, Inc.

Shelby, North Carolina, 28150, United States
Central Florida Eye Associates

Lakeland, Florida, 33805, United States
Central Florida Eye Specialists

DeLand, Florida, 32720, United States
Coastal Research Associates

Roswell, Georgia, 30076, United States
Coldwater Vision Research

Coldwater, Mississippi, 38618, United States
East Coast Institute for Research, LLC

Jacksonville, Florida, 32256, United States
Eye Doctors of Arizona

Phoenix, Arizona, 85028, United States
Eye Research Foundation

Newport Beach, California, 92663, United States
Glaucoma Specialists of South Florida

Delray Beach, Florida, 33484, United States
Kannarr Eye Care LLC

Pittsburg, Kansas, 66762, United States
Las Vegas Eye Institute

Henderson, Nevada, 89052, United States
Lee Shettle Eye

Largo, Florida, 33773, United States
Midwest Eye Center

Cincinnati, Ohio, 45236, United States
North Bay Eye Associates

Petaluma, California, 94954, United States
North Georgia Eye Associates

Gainesville, Georgia, 30501, United States
NorthEast Eye Research Associates, LLC

Westborough, Massachusetts, 01581, United States
Oculus Research, Inc.

Garner, North Carolina, 27529, United States
Orange County Ophthalmology Medical Group

Garden Grove, California, 92843, United States
Piedmont Eye Center

Lynchburg, Virginia, 24502, United States
Rochester Ophthalmological Group

Rochester, New York, 14618, United States
Sacramento Eye Consultants

Sacramento, California, 95815, United States
Scott & Christie and Associates, PC

Cranberry Township, Pennsylvania, 16066, United States
Southern College of Optometry

Memphis, Tennessee, 38104, United States
The Eye Institute of Utah

Salt Lake City, Utah, 84107, United States
The Eye Institute of West Florida

Largo, Florida, 33770, United States
Total Eye Care, PA

Memphis, Tennessee, 38119, United States
Trinity Research Group

Dothan, Alabama, 36301, United States
United Medical Research Institute

Inglewood, California, 90301, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.